Evidence map›Paper›PMID 29348619›Full record

ArticleScientific reports2018

Cytokine-mediated changes in K

Matthew T Dickerson, Avery M Bogart, Molly K Altman, Sarah C Milian, Kelli L Jordan, Prasanna K Dadi, David A Jacobson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Metabolic Stress Shifts the Function of KArchiv der Pharmazie · 2026
    Article
  2. Article
  3. The diabetes-associated KDiabetologia · 2026
    Article
  4. Glycolytic activation of β-cell NaMolecular metabolism · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Role of mitochondrial DNA in diabetes Mellitus Type I and Type II.Saudi journal of biological sciences · 2022
    Review
  9. GNature communications · 2022
    Article
  10. Article
  11. The Role of Mitochondrial Mutations and Chronic Inflammation in Diabetes.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Article
  14. Lactate activation of α-cell KMolecular metabolism · 2020
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Matthew T DickersonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Avery M BogartDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Molly K AltmanDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Sarah C MilianDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Kelli L JordanDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
Prasanna K DadiDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.
David A JacobsonDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA. david.a.jacobson@vanderbilt.edu.
Vanderbilt University · USOhio University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
TRANSGENIC MOUSE/ ES CELL SHARES RESOURCESP60DK020593 · NIDDK · VANDERBILT UNIVERSITY · PI POWERS, ALVIN C · 1986 to 2011
$28.1M
MULTIDISCIPLINARY TRAINING IN MOLECULAR ENDOCRINOLOGYT32DK007563 · NIDDK · VANDERBILT UNIVERSITY · PI Richard M O'Brien · 1988 to 2026
$15.9M
Vanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9M
Vanderbilt/Meharry Initiative for Minority Student DvptR25GM062459 · NIGMS · VANDERBILT UNIVERSITY · PI VELEZ EDWARDS, DIGNA R · 2002 to 2020
$10.4M
Integrated Training in Engineering and DiabetesT32DK101003 · NIDDK · VANDERBILT UNIVERSITY · PI Jamey D. Young · 2014 to 2026
$3.9M
Two-Pore-Domain Potassium Channels as Novel Targets for Modulating Islet Hormone SecretionR01DK097392 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2013 to 2022
$3.3M
Designing selective TALK-1 inhibitors to reduce beta-cell dysfunction in diabetesR01DK115620 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2018 to 2021
$1.6M
LSM880-Airyscan Confocal Microscope for Large Shared ResourceS10OD021630 · OD · VANDERBILT UNIVERSITY · PI WELLS, K. SAM · 2016 to 2016
$560k
Secretagogue Induced Mechanisms Regulating Islet Electrical ActivityK01DK081666 · NIDDK · VANDERBILT UNIVERSITY · PI JACOBSON, DAVID AARON · 2009 to 2012
$505k
NCI NIH HHS P30 CA068485NIDDK NIH HHS K01 DK081666NIDDK NIH HHS P60 DK020593NIDDK NIH HHS R01 DK097392NIDDK NIH HHS R01 DK115620NIDDK NIH HHS T32 DK007563NIDDK NIH HHS T32 DK101003NIDDK NIH HHS U24 DK059637NIGMS NIH HHS R25 GM062459NIH HHS S10 OD021630
6 · The paper itself

Abstract

Cytokines present during low-grade inflammation contribute to β-cell dysfunction and diabetes. Cytokine signaling disrupts β-cell glucose-stimulated Ca

Indexed as

AdultAnimalsCalciumFemaleGene Expression RegulationGlucoseHumansInsulinInsulin-Secreting CellsInsulin SecretionInterferon-gammaInterleukin-1betaIon TransportIslets of LangerhansMaleMiceATP2A2 protein, humanCalciumGlucoseIL1B protein, humanInsulinInterferon-gammaInterleukin-1betaKCNK16 protein, humanPotassiumPotassium Channels, Tandem Pore DomainRNA, MessengerSarcoplasmic Reticulum Calcium-Transporting ATPasesTumor Necrosis Factor-alpha

Identifiers

PMID29348619
PMCPMC5773563
OpenAlexW2783952699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.