Evidence map›Paper›PMID 29348606›Full record

ArticleCell death & disease2018

AMP-activated protein kinase agonist N

Jin Li, Bo Chen, Liping Zhong, Feng Gao, Haibo Zhu, Fengzhong Wang

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  6. Diverse Functions of Autophagy in Liver Physiology and Liver Diseases.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jin LiInstitute of Food Science and Technology, Chinese Academy of Agricultural Sciences (CAAS), 100193, Beijing, China.
Bo ChenInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.
Liping ZhongLife Science College of Tarim University, 843300, Xinjiang, China.
Feng GaoState Key Laboratory for Bioactive Substances and Functions of Natural Medicines and Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China.
Haibo ZhuState Key Laboratory for Bioactive Substances and Functions of Natural Medicines and Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, 100050, Beijing, China. zhuhaibo@imm.ac.cn.
Fengzhong WangInstitute of Food Science and Technology, Chinese Academy of Agricultural Sciences (CAAS), 100193, Beijing, China. wangfengzhong@sina.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNChinese Academy of Agricultural Sciences · CNInstitute of Food Science and Technology · CNTarim University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both AMP-activated protein kinase (AMPK) agonist and inhibitor have been reported to protect against fulminant hepatitis, implying that AMPK may play a complicated role in the development of fulminant hepatitis. In this study, we exploited whether the novel AMPK agonist N

Indexed as

AdenosineAMP-Activated Protein KinasesAnimalsApoptosisHepatitisHumansInflammationMaleMiceAdenosineAMP-Activated Protein Kinases

Identifiers

PMID29348606
PMCPMC5833387
OpenAlexW2788625980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.