ArticleScientific reports2018
Genome and secretome analysis of Pochonia chlamydosporia provide new insight into egg-parasitic mechanisms.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 33 citations in OpenAlex.
- Purpureocillium lilacinum and Pochonia chlamydosporia as biocontrol agents: a comparative review of efficacy, ecology, and integrated application.Archives of microbiology · 2026Review
- Functional diversity and evolutionary strategies in nematophagous fungi and plant parasitic nematodes interactions - a review.Frontiers in plant science · 2026Review
- Identification and Classification of Fungal GPCR Gene Families.Journal of fungi (Basel, Switzerland) · 2025Article
- Dynamic proteomic changes and ultrastructural insights intoFrontiers in cellular and infection microbiology · 2025Article
- Review
- Biological control of the native endophytic fungusFrontiers in microbiology · 2024Article
- Nematicidal glycosylated resorcylic acid lactones from the fungusFrontiers in microbiology · 2024Article
- "Ectomosphere": Insects and Microorganism Interactions.Microorganisms · 2023Review
- Chitosan induces differential transcript usage of chitosanase 3 encoding gene (csn3) in the biocontrol fungus Pochonia chlamydosporia 123.BMC genomics · 2022Article
- Article
- Chitosan modulates Pochonia chlamydosporia gene expression during nematode egg parasitism.Environmental microbiology · 2021Article
- Putative LysM Effectors Contribute to Fungal Lifestyle.International journal of molecular sciences · 2021Article
- Increased Pathogenicity of the Nematophagous FungusFrontiers in fungal biology · 2021Article
- Review
Corrections and comments
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Authors and funding
18 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pochonia chlamydosporia infects eggs and females of economically important plant-parasitic nematodes. The fungal isolates parasitizing different nematodes are genetically distinct. To understand their intraspecific genetic differentiation, parasitic mechanisms, and adaptive evolution, we assembled seven putative chromosomes of P. chlamydosporia strain 170 isolated from root-knot nematode eggs (~44 Mb, including 7.19% of transposable elements) and compared them with the genome of the strain 123 (~41 Mb) isolated from cereal cyst nematode. We focus on secretomes of the fungus, which play important roles in pathogenicity and fungus-host/environment interactions, and identified 1,750 secreted proteins, with a high proportion of carboxypeptidases, subtilisins, and chitinases. We analyzed the phylogenies of these genes and predicted new pathogenic molecules. By comparative transcriptome analysis, we found that secreted proteins involved in responses to nutrient stress are mainly comprised of proteases and glycoside hydrolases. Moreover, 32 secreted proteins undergoing positive selection and 71 duplicated gene pairs encoding secreted proteins are identified. Two duplicated pairs encoding secreted glycosyl hydrolases (GH30), which may be related to fungal endophytic process and lost in many insect-pathogenic fungi but exist in nematophagous fungi, are putatively acquired from bacteria by horizontal gene transfer. The results help understanding genetic origins and evolution of parasitism-related genes.
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