Evidence map›Paper›PMID 29348490›Full record

Observational studyBritish journal of cancer2018

Robot-assisted radical prostatectomy vs laparoscopic and open retropubic radical prostatectomy: functional outcomes 18 months after diagnosis from a national cohort study in England.

Julie Nossiter, Arunan Sujenthiran, Susan C Charman, Paul J Cathcart, Ajay Aggarwal, Heather Payne, Noel W Clarke, Jan van der Meulen

Abstract readComparative StudyObservational Study
In one paragraph

Observational study in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julie NossiterDepartment of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Arunan SujenthiranClinical Effectiveness Unit, Royal College of Surgeons of England, London WC2A 3PE, UK.
Susan C CharmanDepartment of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Paul J CathcartDepartment of Urology, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Ajay AggarwalDepartment of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.
Heather PayneDepartment of Oncology, University College London Hospitals NHS Foundation Trust, London NW1 2BU, UK.
Noel W ClarkeDepartment of Urology, The Christie, Manchester M20 4BX, UK.
Jan van der MeulenDepartment of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK.

Funding

Department of Health DRF-2014-07-064
6 · The paper itself

Abstract

backgroundRobot-assisted radical prostatectomy (RARP) has been rapidly adopted without robust evidence comparing its functional outcomes against laparoscopic radical prostatectomy (LRP) or open retropubic radical prostatectomy (ORP) approaches. This study compared patient-reported functional outcomes following RARP, LRP or ORP.

methodsAll men diagnosed with prostate cancer in England during April - October 2014 who underwent radical prostatectomy were identified from the National Prostate Cancer Audit and mailed a questionnaire 18 months after diagnosis. Group differences in patient-reported sexual, urinary, bowel and hormonal function (EPIC-26 domain scores) and generic health-related quality of life (HRQoL; EQ-5D-5L scores), with adjustment for patient and tumour characteristics, were estimated using linear regression.

resultsIn all, 2219 men (77.0%) responded; 1310 (59.0%) had RARP, 487 (21.9%) LRP and 422 (19.0%) ORP. RARP was associated with slightly higher adjusted mean EPIC-26 sexual function scores compared with LRP (3·5 point difference; 95% CI: 1.1-5.9, P=0.004) or ORP (4.0 point difference; 95% CI: 1.5-6.5, P=0.002), which did not meet the threshold for a minimal clinically important difference (10-12 points). There were no significant differences in other EPIC-26 domain scores or HRQoL.

conclusionsIt is unlikely that the rapid adoption of RARP in the English NHS has produced substantial improvements in functional outcomes for patients.

Indexed as

AgedCohort StudiesHumansLaparoscopyLinear ModelsMaleMiddle AgedProstatectomyProstatic NeoplasmsQuality of LifeRobotic Surgical ProceduresSurveys and Questionnaires

Identifiers

PMID29348490
PMCPMC5830598

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.