Evidence map›Paper›PMID 29348484›Full record

ArticleScientific reports2018

Activation of Ca

Jie Gu, Shuya Dai, Yanmin Liu, Haitao Liu, Yao Zhang, Xingqi Ji, Feng Yu, Yang Zhou, Liang Chen, William Ka Fai Tse and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Mechanisms of Heavy Metal Cadmium (Cd)-Induced Malignancy.Biological trace element research · 2025
    Review
  7. Review
  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  9. Review
  10. Article
  11. Cadmium Disrupted ER CaInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. l-ornithine activates CaCellular signalling · 2020
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Jie GuInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Shuya DaiInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Yanmin LiuInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Haitao LiuInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Yao ZhangMedical Section, The Third Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Xingqi JiInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Feng YuInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Yang ZhouInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Liang ChenInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
William Ka Fai TseFaculty of Agriculture, Kyushu University, Fukuoka, Japan.
Chris Kong Chu WongDepartment of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Binghai ChenDepartment of urology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 212000, China.
Haifeng ShiInstitute of Life Science, Jiangsu University, Zhenjiang, Jiangsu, 212000, China. shihf@ujs.edu.cn.
Jiangsu University · CNAffiliated Hospital of Jiangsu University · CNHong Kong Baptist University · HKKyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse renal tubular epithelial cells (mRTECs) to clarify Cd-induced toxicity and signaling pathways. Moreover, we proposed to elucidate the prevent effect of activation of Ca

Indexed as

Signal TransductionAnimalsApoptosisAutophagyCadmiumCell LineEpithelial CellsHumansIntracellular SpaceKidney Tubules, ProximalMAP Kinase Signaling SystemMiceModels, BiologicalReactive Oxygen SpeciesReceptors, Calcium-SensingCadmiumReactive Oxygen SpeciesReceptors, Calcium-Sensing

Identifiers

PMID29348484
PMCPMC5773512
OpenAlexW2783143330

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.