Evidence map›Paper›PMID 29348432›Full record

ArticleScientific reports2018

Genome-wide association study of self-reported food reactions in Japanese identifies shrimp and peach specific loci in the HLA-DR/DQ gene region.

Seik-Soon Khor, Ryoko Morino, Kazuyuki Nakazono, Shigeo Kamitsuji, Masanori Akita, Maiko Kawajiri, Tatsuya Yamasaki, Azusa Kami, Yuria Hoshi, Asami Tada and 7 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Trial
  5. Review
  6. Article
  7. Article
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  11. Article
  12. Article
  13. Review
  14. Multi-omics profiling approach in food allergy.The World Allergy Organization journal · 2023
    Review
  15. Recent insights into the mechanisms of anaphylaxis.Current opinion in immunology · 2023
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Identification of key genes in allergic rhinitis by bioinformatics analysis.The Journal of international medical research · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Seik-Soon KhorDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
Ryoko MorinoEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Kazuyuki NakazonoStaGen Co., Ltd., Taito-ku, Tokyo, 111-0051, Japan.
Shigeo KamitsujiStaGen Co., Ltd., Taito-ku, Tokyo, 111-0051, Japan.
Masanori AkitaEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Maiko KawajiriEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Tatsuya YamasakiLife Science Group, Healthcare Division, Department of Healthcare Business, MTI Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Azusa KamiEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Yuria HoshiLife Science Group, Healthcare Division, Department of Healthcare Business, MTI Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Asami TadaEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Kenichi IshikawaEverGene Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Maaya HineLunaLuna Division, Department of Healthcare Business, MTI Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Miki KobayashiLunaLuna Division, Department of Healthcare Business, MTI Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Nami KurumeLunaLuna Division, Department of Healthcare Business, MTI Ltd., Shinjuku-ku, Tokyo, 163-1435, Japan.
Naoyuki KamataniStaGen Co., Ltd., Taito-ku, Tokyo, 111-0051, Japan.
Katsushi TokunagaDepartment of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, 113-0033, Japan.
Todd A JohnsonStaGen Co., Ltd., Taito-ku, Tokyo, 111-0051, Japan. todd.johnson@stagen.co.jp.ORCID http://orcid.org/0000-0003-3377-6692
StaGen (Japan) · JPMonohakobi Technology Institute (Japan) · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy is an increasingly important health problem in the world. Several genome-wide association studies (GWAS) focused on European ancestry samples have identified food allergy-specific loci in the HLA class II region. We conducted GWAS of self-reported reactivity with common foods using the data from 11011 Japanese women and identified shrimp and peach allergy-specific loci in the HLA-DR/DQ gene region tagged by rs74995702 (P = 6.30 × 10

Indexed as

AllelesGenome-Wide Association StudyAdultAllergensAnimalsAnostracaComputational BiologyCross ReactionsEpitopesFemaleFood HypersensitivityGenetic Predisposition to DiseaseHLA-DQ AntigensHLA-DR AntigensHumansJapanAllergensEpitopesHLA-DQ AntigensHLA-DR Antigens

Identifiers

PMID29348432
PMCPMC5773682
OpenAlexW2784105271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.