ArticleScientific reports2018
Synthesis of Luminescent Carbon Dots with Ultrahigh Quantum Yield and Inherent Folate Receptor-Positive Cancer Cell Targetability.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed, 315 citations in OpenAlex.
- Article
- Carbon Dots: Emerging Nanomaterials for Ovarian Cancer Diagnosis and Therapy.Current drug targets · 2026Review
- Facile One-Pot Synthesis of Folic Acid-Derived Carbon Dots for Selective "on-off-on" Fluorescence Detection of AgJournal of fluorescence · 2026Article
- Functionalized Carbon Dots from Bio-Based Precursors as Promising Fluorescent Probes for Cancer Cell Imaging.International journal of molecular sciences · 2025Article
- One-Step Synthesized Folic Acid-Based Carbon Dots: A Biocompatible Nanomaterial for the Treatment of Bacterial Infections in Lung Pathologies.Nanomaterials (Basel, Switzerland) · 2025Article
- Effective Determination of Diosmin Using Nitrogen Doped Carbon Dots as Probe Based on Internal Filtering Effect.Journal of fluorescence · 2025Review
- Boron carbide nanoparticles for boron neutron capture therapy.RSC advances · 2025Article
- Review
- Sustainable Carbon Dots Loaded into Carboxymethylcellulose Based Hydrogels for Uterine Cancer Bioimaging.Pharmaceutics · 2024Article
- Carbon Dots: A Review with Focus on Sustainability.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Anticancer activity of quantum size carbon dots: opportunities and challenges.Discover nano · 2024Review
- Ultrasound-assisted encapsulating folic acid-based carbon quantum dots within breast cancer cell-derived exosomes as a co-receptors-mediated anticancer nanocarrier for enhanced breast cancer therapy.Scientific reports · 2024Article
- Fluorescent carbon dots for discriminating cell types: a review.Analytical and bioanalytical chemistry · 2024Review
- Photoluminescence quantum yield of carbon dots: emission due to multiple centersNanoscale advances · 2024Article
- Carbon Nanomaterial Fluorescent Probes and Their Biological Applications.Chemical reviews · 2024Review
- Applications of Quantum Dots in Preventive Oncology.Asian Pacific journal of cancer prevention : APJCP · 2024Review
- Tumor diagnosis using carbon-based quantum dots: Detection based on the hallmarks of cancer.Bioactive materials · 2024Review
- Package delivered: folate receptor-mediated transporters in cancer therapy and diagnosis.Chemical science · 2024Review
- High Quantum Yield Amino Acid Carbon Quantum Dots with Unparalleled Refractive Index.ACS nano · 2024Article
- Cancer Cell Targeting Via Selective Transferrin Receptor Labeling Using Protein-Derived Carbon Dots.ACS omega · 2024Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs) have a wide range of applications in chemical, physical and biomedical research fields. We are particularly interested in the use of CDs as fluorescence nanomaterials for targeted tumor cell imaging. One of the important aspects of success is to enhance the fluorescence quantum yields (QY) of CDs as well as increase their targetability to tumor cells. However, most of the reported CDs are limited by relative low QY. In the current study, for the first time, one-step synthesis of highly luminescent CDs by using folic acid (FA) as single precursor was obtained in natural water through hydrothermal method. The as-prepared CDs exhibited QY as high as 94.5% in water, which is even higher than most of organic fluorescent dyes. The obtained CDs showed excellent photoluminescent activity, high photostability and favorable biocompatibility. The FA residuals in CDs led to extraordinary targetability to cancer cells and promoted folate receptor-mediated cellular uptake successfully, which holds a great potential in biological and bioimaging studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.