ArticleScientific reports2018
In vivo Microscopic Photoacoustic Spectroscopy for Non-Invasive Glucose Monitoring Invulnerable to Skin Secretion Products.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 158 citations in OpenAlex.
- Photoacoustic Resonators for Non-Invasive Blood Glucose Detection Through Photoacoustic Spectroscopy: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- Photoacoustic Fingerprinting for Robust Molecular Imaging.bioRxiv : the preprint server for biology · 2026Article
- A Single-Wavelength Near-Infrared Photoacoustic Spectroscopy for Noninvasive Glucose Detection Using Machine Learning.Bioengineering (Basel, Switzerland) · 2026Article
- Photoacoustic Noninvasive Blood Glucose Monitoring: A Review of Systems and Strategies for Robust Glucose Concentration Estimation, with Perspectives on Miniaturization and Wearability.Sensors (Basel, Switzerland) · 2026Review
- Design of a microwave sensor for non-invasive monitoring of blood glucose level with high sensitivity using electromagnetic properties.Scientific reports · 2026Article
- Blood component analysis using mid-infrared photoacoustic spectroscopy based on ultrasound detection: glucose analysis trial.Journal of biomedical optics · 2025Article
- Light and metabolism: label-free optical imaging of metabolic activities in biological systems [Invited].Biomedical optics express · 2025Review
- Optical Non-Invasive Glucose Monitoring Using Aqueous Humor: A Review.Sensors (Basel, Switzerland) · 2025Review
- Advanced vibrational microscopes for life science.Nature methods · 2025Review
- The Optimization of a T-Cell Resonator: Towards Highly Sensitive Photoacoustic Spectroscopy for Noninvasive Blood Glucose Detection.Biosensors · 2025Article
- Clinical evaluation of a polarization-based optical noninvasive glucose sensing system.Scientific reports · 2025Article
- Subcutaneous depth-selective spectral imaging with mμSORS enables noninvasive glucose monitoring.Nature metabolism · 2025Article
- Deep Learning-Enhanced Portable Chemiluminescence Biosensor: 3D-Printed, Smartphone-Integrated Platform for Glucose Detection.Bioengineering (Basel, Switzerland) · 2025Article
- Photoacoustic imaging: a unique imaging examination for the assessment of diabetic vascular disease.Frontiers in clinical diabetes and healthcare · 2025Review
- Additively manufactured microwave sensor for glucose level detection in saliva.Scientific reports · 2024Article
- Highly Sensitive Perovskite Photoplethysmography Sensor for Blood Glucose Sensing Using Machine Learning Techniques.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Article
- Quantitative blood glucose detection influenced by various factors based on the fusion of photoacoustic temporal spectroscopy with deep convolutional neural networks.Biomedical optics express · 2024Article
- Augmenting authenticity for non-invasive in vivo detection of random blood glucose with photoacoustic spectroscopy using Kernel-based ridge regression.Scientific reports · 2024Article
- Non-invasive measurements of blood glucose levels by time-gating mid-infrared optoacoustic signals.Nature metabolism · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Photoacoustic spectroscopy has been shown to be a promising tool for non-invasive blood glucose monitoring. However, the repeatability of such a method is susceptible to changes in skin condition, which is dependent on hand washing and drying due to the high absorption of infrared excitation light to the skin secretion products or water. In this paper, we present a method to meet the challenges of mid-infrared photoacoustic spectroscopy for non-invasive glucose monitoring. By obtaining the microscopic spatial information of skin during the spectroscopy measurement, the skin region where the infrared spectra is insensitive to skin condition can be locally selected, which enables reliable prediction of the blood glucose level from the photoacoustic spectroscopy signals. Our raster-scan imaging showed that the skin condition for in vivo spectroscopic glucose monitoring had significant inhomogeneities and large variability in the probing area where the signal was acquired. However, the selective localization of the probing led to a reduction in the effects of variability due to the skin secretion product. Looking forward, this technology has broader applications not only in continuous glucose monitoring for diabetic patient care, but in forensic science, the diagnosis of malfunctioning sweat pores, and the discrimination of tumors extracted via biopsy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.