Evidence map›Paper›PMID 29348191›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Multimodal Encoding of Novelty, Reward, and Learning in the Primate Nucleus Basalis of Meynert.

Clarissa Martinez-Rubio, Angelique C Paulk, Eric J McDonald, Alik S Widge, Emad N Eskandar

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Role of Cholinergic Signaling in Alzheimer's Disease.Molecules (Basel, Switzerland) · 2022
    Review
  6. The neural circuits of monogamous behavior.Frontiers in neural circuits · 2022
    Review
  7. Article
  8. Article
  9. Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Clarissa Martinez-RubioNayef Al-Rodhan Laboratories, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.
Angelique C PaulkNayef Al-Rodhan Laboratories, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.ORCID 0000-0002-4413-3417
Eric J McDonaldNayef Al-Rodhan Laboratories, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.ORCID 0000-0003-0914-4038
Alik S WidgeDepartment of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129.ORCID 0000-0001-8510-341X
Emad N EskandarNayef Al-Rodhan Laboratories, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, eeskandar@mgh.harvard.edu.ORCID 0000-0003-4743-2938
Harvard University · USAlbert Einstein College of Medicine · US

Funding

Using microstimulation to map prefrontal fear modules in the ratP50MH086400 · NIMH · UNIVERSITY OF ROCHESTER · PI GRACE, ANTHONY A · 2009 to 2013
$10.3M
Neostriatum in Learning and MemoryR01EY017658 · NEI · MASSACHUSETTS GENERAL HOSPITAL · PI ESKANDAR, EMAD N · 2007 to 2013
$2.7M
Striatal Deep Brain Stimulation for Learning EnhancementR01DA026297 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI ESKANDAR, EMAD N · 2008 to 2011
$1.5M
Inhibitory single neuron control of human epilepsyF32NS083208 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AHMED, OMAR JAMIL · 2013 to 2013
$54k
NEI NIH HHS R01 EY017658NIDA NIH HHS R01 DA026297NIMH NIH HHS P50 MH086400NINDS NIH HHS F32 NS083208
6 · The paper itself

Abstract

Associative learning is crucial for daily function, involving a complex network of brain regions. One region, the nucleus basalis of Meynert (NBM), is a highly interconnected, largely cholinergic structure implicated in multiple aspects of learning. We show that single neurons in the NBM of nonhuman primates (NHPs;

Indexed as

RewardAnimalsAssociation LearningBasal Nucleus of MeynertMacaca mulattaMaleNeuronsencoding cognitive statelearninglocal field potentialnucleus basalis of Meynertsingle neuron activity

Identifiers

PMID29348191
PMCPMC5824738
OpenAlexW2784904975

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.