Evidence map›Paper›PMID 29348168›Full record

ArticleThe Journal of biological chemistry2018

The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A

Yibin Lin, Mikhail Bogdanov, Shuo Lu, Ziqiang Guan, William Margolin, Jerrold Weiss, Lei Zheng

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Dark Side ofJournal of the American Chemical Society · 2026
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  20. Group IIA-Secreted Phospholipase AInfection and immunity · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yibin LinFrom the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and.
Mikhail Bogdanovthe Departments of Biochemistry and Molecular Biology and.
Shuo LuFrom the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and.
Ziqiang Guanthe Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, and.
William MargolinMicrobiology and Molecular Genetics, University of Texas McGovern Medical School, Houston, Texas 77030.
Jerrold Weissthe Inflammation Program and Departments of Internal Medicine and Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242.
Lei ZhengFrom the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and lei.zheng@uth.tmc.edu.
Duke University · USUniversity of Iowa · US

Funding

STEROL LIPIDSU54GM069338 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 2003 to 2013
$72.2M
Targeting and assembly of E. coli division proteinsR01GM061074 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MARGOLIN, WILLIAM · 2000 to 2018
$5.7M
Ca2+ Transport Mechanism of CaCA Protein FamilyR01GM097290 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHENG, LEI · 2011 to 2015
$1.7M
Phospholipid Metabolism in Cell MembraneR01GM098572 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ZHENG, LEI · 2012 to 2015
$1.2M
NIGMS NIH HHS R01 GM061074NIGMS NIH HHS R01 GM097290NIGMS NIH HHS R01 GM098572NIGMS NIH HHS U54 GM069338
6 · The paper itself

Abstract

Secretory phospholipases A

Indexed as

Host-Pathogen InteractionsAcyltransferasesAnimalsCell MembraneEnzyme ActivationEscherichia coliEscherichia coli ProteinsPhospholipases A2PhospholipidsPhospholipid Transfer ProteinsAcyltransferasesEscherichia coli ProteinsLplT protein, E coliPhospholipases A2PhospholipidsPhospholipid Transfer Proteinsbacteriabacterial resistancelysophospholipidmembrane biogenesismembrane envelopemembrane lipidmembrane structureouter membrane asymmetryphospholipase Aphospholipase A2phospholipid turnover

Identifiers

PMID29348168
PMCPMC5836115
OpenAlexW2785134819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.