ArticleBMC gastroenterology2018
Uninvestigated dyspepsia and associated factors of patients with gastrointestinal disorders in Dessie Referral Hospital, Northeast Ethiopia.
Article in BMC gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Prevalence and associated risk factors of Helicobacter pylori infection in East Africa: a systematic review and meta-analysis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Pooled it
- Helicobacter pylori infections in Ethiopia; prevalence and associated factors: a systematic review and meta-analysis.BMC gastroenterology · 2019Pooled it
- Prevalence of undiagnosed dyspepsia, associated factors, and its relationship with quality of life among undergraduate health program students at Makerere University in Uganda.BMC gastroenterology · 2026Article
- Article
- Health-related quality of life in patients with dyspepsia presenting at the University of Benin Teaching Hospital, Benin City, South-South Nigeria: a cross-sectional study.The Pan African medical journal · 2024Article
- Abdominal Pain of Functional Gastrointestinal Disorders in Dietary Diversity Patterns and Its Determinants among Healthy Adults in Jimma City, Southwest Ethiopia.Ethiopian journal of health sciences · 2023Article
- Indications and Findings of Upper Gastrointestinal Endoscopy at a Tertiary Hospital in Ethiopia: A Cross-Sectional Study.Clinical and experimental gastroenterology · 2023Article
- Community prevalence ofHeliyon · 2022Article
- Article
- The prevalence of uninvestigated dyspepsia and the association of physical exercise with quality of life of uninvestigated dyspepsia patients in Indonesia: An internet-based survey.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Changes in the Seroprevalence ofMedicina (Kaunas, Lithuania) · 2021Article
- Prevalence and sociodemographic determinants of dyspepsia in the general population of Rwanda.BMJ open gastroenterology · 2020Article
- The Psychotic Impact of Helicobacter pylori Gastritis and Functional Dyspepsia on Depression: A Systematic Review.Cureus · 2019Review
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3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The aim of this study was to determine the prevalence of uninvestigated dyspepsia (UD) using Rome III criteria, associated risk factors and self-reported dyspepsia symptoms' correlation with H. pylori infection.
methodsA cross-sectional study was conducted among randomly selected 318 out patients with gastrointestinal complaints during the period from September 1 to December 30, 2015. All patients completed a questionnaire for collecting data regarding sociodemographic, lifestyle and functional gastrointestinal disorders. Diagnosis of dyspepsia was made according to the Rome III criteria. H. pylori infection was assessed using stool antigen test. SPSS version 20.0 statistical software package was used for data analysis.
resultsFrom a total of 318 patients, 48.4% had UD according to Rome III criteria; with 42.1% symptoms of epigastric pain/burning, 26.1% postprandial fullness and 22.6% early satiation. Epigastric pain/burning (AOR = 1.92, 95% CI 1.07-3.43), early satiation (AOR = 2.68, 95% CI 1.38-5.20) and belching (AOR = 4.7, 95% CI 1.54-14.40) were significantly correlated with H. pylori infection. H. pylori infection (AOR = 4.33, 95% CI 2.41-7.76) and aspirin/NSAIDs consumption (AOR = 5.29, 95% CI 2.82-9.93) were independent risk factors for UD. However, consumption of raw fruits/ vegetables at least once a week (AOR = 0.48, 95% CI 0.24-0.98) and taking two or more cups of tea a day (AOR = 0.339, 95% CI 0.17-0.70) were inversely associated with UD.
conclusionsUD is highly prevalent among adults with gastrointestinal complaints. H. pylori infection is significantly associated with UD and correlates with its symptoms. Individuals with epigastric pain/burning, early satiation and belching should be primary focus of H. pylori infection diagnosis and treatment. The role of consumption of tea, raw fruits and vegetables on dyspepsia needs further large scale study.
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