Evidence map›Paper›PMID 29347972›Full record

ArticleBMC research notes2018

Extending the utility of the WHO recommended assay for direct detection of enteroviruses from clinical specimen for resolving poliovirus co-infection.

Temitope Oluwasegun Cephas Faleye, Moses Olubusuyi Adewumi, Naomi Princess Ozegbe, Oluwaseun Elijah Ogunsakin, Grace Ariyo, Faith Wuraola Adeshina, Oluwaseun Sarah Ogunga, Similoluwa Deborah Oluwadare, Johnson Adekunle Adeniji

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Temitope Oluwasegun Cephas FaleyeDepartment of Virology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Moses Olubusuyi AdewumiDepartment of Virology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria.
Naomi Princess OzegbeDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Oluwaseun Elijah OgunsakinDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Grace AriyoDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Faith Wuraola AdeshinaDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Oluwaseun Sarah OgungaDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Similoluwa Deborah OluwadareDepartment of Microbiology, Faculty of Science, Ekiti State University, Ado Ekiti, Ekiti State, Nigeria.
Johnson Adekunle AdenijiDepartment of Virology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeria. adek1808@yahoo.com.
Ekiti State University · NGUniversity of Ibadan · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn a polio-free world there might be reduced funding for poliovirus surveillance. There is therefore the need to ensure that enterovirologist globally, especially those outside the global polio laboratory network, can participate in poliovirus surveillance without neglecting their enterovirus type of interest. To accomplish this, assays are needed that allow such active participation.

resultsIn this study we describes a sensitive and specific utility extension of the recently recommended WHO RT-snPCR assay that enables independent detection of the three poliovirus types especially in cases of co-infection. More importantly, it piggy-backs on the first round PCR product of the WHO recommended assay and consequently ensures that enterovirologists interested in nonpolio enteroviruses can continue their investigations, and contribute significantly and specifically to poliovirus surveillance, by using the excess of their first round PCR product.

Indexed as

AlgorithmsCoinfectionEnterovirusEnterovirus InfectionsFecesHumansPoliomyelitisPoliovirusPolymerase Chain ReactionPopulation SurveillanceReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityWorld Health OrganizationEnterovirusesNigeriaPoliovirusesSurveillanceWHO

Identifiers

PMID29347972
PMCPMC5774100
OpenAlexW2951785827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.