ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2017
Preventive chemotherapy to control soil-transmitted helminthiasis averted more than 500 000 DALYs in 2015.
Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Interventions to improve water, sanitation, and hygiene for preventing soil-transmitted helminth infection.The Cochrane database of systematic reviews · 2022Pooled it
- Maternal Hookworm Infection and Its Effects on Maternal Health: A Systematic Review and Meta-Analysis.The American journal of tropical medicine and hygiene · 2020Pooled it
- Epidemiology of soil-transmitted helminths following sustained implementation of routine preventive chemotherapy: Demographics and baseline results of a cluster randomised trial in southern Malawi.PLoS neglected tropical diseases · 2021Trial
- Diagnostic performance of a single and duplicate Kato-Katz, Mini-FLOTAC, FECPAKG2 and qPCR for the detection and quantification of soil-transmitted helminths in three endemic countries.PLoS neglected tropical diseases · 2019Trial
- Comprehensive evaluation of stool-based diagnostic methods and benzimidazole resistance markers to assess drug efficacy and detect the emergence of anthelmintic resistance: A Starworms study protocol.PLoS neglected tropical diseases · 2018Trial
- Post-market surveillance of albendazole tablet brands in Kenya: Implications for deworming programs and clinical outcomes.PLoS neglected tropical diseases · 2026Article
- Persistence of soil-transmitted helminth infections among school-age children after multiple rounds of mass drug administration in Machame Narumu, Hai District, north-eastern Tanzania.BMC infectious diseases · 2026Article
- Economic evaluation of primary health care integration and targeted mass drug administration in counties in western Kenya.Frontiers in health services · 2026Article
- Global burden of soil-transmitted helminth infections, 1990-2021.Infectious diseases of poverty · 2024Article
- Article
- Reduction in DALYs lost due to soil-transmitted helminthiases and schistosomiasis from 2000 to 2019 is parallel to the increase in coverage of the global control programmes.PLoS neglected tropical diseases · 2022Article
- Impact of preventive chemotherapy on transmission of soil-transmitted helminth infections in Pemba Island, United Republic of Tanzania, 1994-2021.PLoS neglected tropical diseases · 2022Article
- Effects of deworming medication on anaemia among children aged 6-59 months in sub-Saharan Africa.Parasites & vectors · 2022Article
- Establishing control and breaking transmission: the importance of accurately classifying cure following treatment for soil-transmitted helminths.The Lancet regional health. Western Pacific · 2021Article
- Are current preventive chemotherapy strategies for controlling and eliminating neglected tropical diseases cost-effective?BMJ global health · 2021Review
- Review
- New global targets for NTDs in the WHO roadmap 2021-2030.PLoS neglected tropical diseases · 2021Article
- Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: Results from a retrospective cohort.PLoS neglected tropical diseases · 2021Article
- Nutrition and the Gut Microbiota in 10- to 18-Month-Old Children Living in Urban Slums of Mumbai, India.mSphere · 2020Article
- The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030.PLoS neglected tropical diseases · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Background: Preventive chemotherapy (PC), the large-scale administration of anthelminthics, is recommended by the World Health Organization (WHO) for the control of soil-transmitted helminthiasis (STH). Since 2010, donated anthelminthics for STH have boosted the implementation of PC programmes in children, achieving global coverage of more than 60% in 2015. The WHO Global Health Estimates attribute an annual loss of over 3.3 million disability-adjusted life-years (DALYs) to STH. The aim of this study is to estimate the impact of PC programmes on child morbidity. Method: We used data from the WHO Global Health Estimates, national coverage data on PC and the results of an evaluation of the impact of PC in 17 countries on morbidity previously conducted by our group. Results: We estimated that the implementation of PC averted in 2015 over 44% of the DALYs that would have been caused in children by STH without the control intervention. A reduction in morbidity of over 75% is expected, if the global target is reached in 2020. If the programme is subsequently maintained, morbidity from STH will be almost totally removed by 2025. Conclusions: In endemic areas, preventive chemotherapy provides a significant health benefit. We consider this estimation potentially useful to evaluate the cost utility of the investment made by several endemic countries on PC to control STH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.