Evidence map›Paper›PMID 29346579›Full record

Trial reportPain medicine (Malden, Mass.)2018

Web-Based Cognitive Behavior Therapy for Chronic Pain Patients with Aberrant Drug-Related Behavior: Outcomes from a Randomized Controlled Trial.

Honoria Guarino, Chunki Fong, Lisa A Marsch, Michelle C Acosta, Cassandra Syckes, Sarah K Moore, Ricardo A Cruciani, Russell K Portenoy, Dennis C Turk, Andrew Rosenblum

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pain medicine (Malden, Mass.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Article
  9. Momentary mindfulness versus distraction coping messages to reduce cannabis craving among young adults: A microrandomized trial.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Honoria GuarinoNational Development and Research Institutes (NDRI), Inc., New York, New York.
Chunki FongNational Development and Research Institutes (NDRI), Inc., New York, New York.
Lisa A MarschCenter for Technology and Behavioral Health, Geisel School of Medicine at Dartmouth College, Lebanon, New Hampshire.
Michelle C AcostaNational Development and Research Institutes (NDRI), Inc., New York, New York.
Cassandra SyckesNational Development and Research Institutes (NDRI), Inc., New York, New York.
Sarah K MooreOpioid Acumen Consulting, Brooklyn, New York.
Ricardo A CrucianiDepartment of Neurology, Drexel University College of Medicine, Philadelphia, Pennsylvania.
Russell K PortenoyMJHS Institute for Innovation in Palliative Care, New York, New York.
Dennis C TurkDepartment of Anesthesiology & Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
Andrew RosenblumNational Development and Research Institutes (NDRI), Inc., New York, New York.
National Development and Research Institutes · USAcumen · USDartmouth College · USDrexel University · USInstitute for Family Health · USUniversity of Washington · US

Funding

Treatment Development & Evaluation CoreP30DA029926 · NIDA · DARTMOUTH COLLEGE · PI Lisa A. Marsch · 2011 to 2026
$21.5M
Web-based CBT for Opioid-treated, Chronic Pain Patients with Aberrant BehaviorR01DA026887 · NIDA · NATIONAL DEVELOPMENT AND RESEARCH INSTITUTES, INC. · PI MARSCH, LISA A., ROSENBLUM, ANDREW BRUCE · 2010 to 2013
$2.3M
NIDA NIH HHS P30 DA029926NIDA NIH HHS R01 DA026887
6 · The paper itself

Abstract

Objective: There is high unmet need for effective behavioral treatments for chronic pain patients at risk for or with demonstrated histories of opioid misuse. Despite growing evidence supporting technology-based delivery of self-management interventions for chronic pain, very few such programs target co-occurring chronic pain and aberrant drug-related behavior. This randomized controlled trial evaluated the effectiveness of a novel, web-based self-management intervention, grounded in cognitive behavior therapy, for chronic pain patients with aberrant drug-related behavior. Methods: Opioid-treated chronic pain patients at a specialty pain practice who screened positive for aberrant drug-related behavior (N = 110) were randomized to receive treatment as usual plus the web-based program or treatment as usual alone. The primary outcomes of pain severity, pain interference, and aberrant drug-related behavior, and the secondary outcomes of pain catastrophizing and pain-related emergency department visits, were assessed during the 12-week intervention and at one and three months postintervention. Results: Patients assigned to use the web-based program reported significantly greater reductions in aberrant drug-related behavior, pain catastrophizing, and pain-related emergency department visits-but not pain severity or pain interference-relative to those assigned to treatment as usual. The positive outcomes were observed during the 12-week intervention and for three months postintervention. Conclusions: A web-based self-management program, when delivered in conjunction with standard specialty pain treatment, was effective in reducing chronic pain patients' aberrant drug-related behavior, pain catastrophizing, and emergency department visits for pain. Technology-based self-management tools may be a promising therapeutic approach for the vulnerable group of chronic pain patients who have problems managing their opioid medication.

Indexed as

InternetPain ManagementAdultAnalgesics, OpioidBehavior TherapyCatastrophizationChronic PainCognitive Behavioral TherapyFemaleHumansMaleMiddle AgedAnalgesics, Opioid

Identifiers

PMID29346579
PMCPMC6294413
OpenAlexW2782864666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.