ArticlePLoS neglected tropical diseases2018
Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique.
Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Continental Prevalence of Tuberculosis Infection and Associated Risk Factors From African Cattle: Systematic Review and Meta-Analysis.Veterinary medicine and science · 2026Pooled it
- Genetic diversity of Mycobacterium bovis in dairy products and cattle tissues from northwest Iran using a 12-locus MIRU-VNTR approach.Scientific reports · 2026Article
- Insight into the genetic diversity ofMicrobiology spectrum · 2026Article
- Genotyping of Mycobacterium tuberculosis complex isolated from humans and animals in northeastern Iran.Scientific reports · 2023Article
- First Insight into Diversity of Minisatellite Loci inDiagnostics (Basel, Switzerland) · 2023Article
- Article
- Geo-epidemiology of animal tuberculosis andFrontiers in microbiology · 2023Article
- Spoligotype analysis ofZoonoses and public health · 2022Article
- Article
- Molecular characterization ofIranian journal of veterinary research · 2022Article
- Population structure and transmission ofMicrobial genomics · 2021Article
- Microbial Safety of Milk Production and Fermented Dairy Products in Africa.Microorganisms · 2020Review
- Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa.BMC microbiology · 2020Article
- Evolutionary analysis of Mycobacterium bovis genotypes across Africa suggests co-evolution with livestock and humans.PLoS neglected tropical diseases · 2020Article
- Genotype diversity and distribution of Mycobacterium bovis from livestock in a small, high-risk area in northeastern Sicily, Italy.PLoS neglected tropical diseases · 2019Article
- Molecular epidemiology of cattle tuberculosis in Mexico through whole-genome sequencing and spoligotyping.PloS one · 2018Article
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17 authors.
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Abstract
Bovine tuberculosis is a zoonotic disease with largely unknown impact in Africa, with risk factors such as HIV and direct contact with animals or consumption of Mycobacterium bovis infected animal products. In order to understand and quantify this risk and design intervention strategies, good epidemiological studies are needed. Such studies can include molecular typing of M. bovis isolates. The aim of this study was to apply these tools to provide novel information concerning the distribution of bovine tuberculosis in cattle in Mozambique and thereby provide relevant information to guide policy development and strategies to contain the disease in livestock, and reduce the risk associated with transmission to humans. A collection of 178 M. bovis isolates was obtained from cattle in Mozambique. Using spoligotyping and regions of difference analysis, we classified the isolates into clonal complexes, thus reporting the first characterisation of M. bovis strains in this region. Data from MIRU-VNTR typing was used to compare isolates from a number of African countries, revealing a deeply geographically structured diversity of M. bovis. Eastern Africa appears to show high diversity, suggesting deep evolution in that region. The diversity of M. bovis in Africa does not seem to be a function of recent importation of animals, but is probably maintained within each particular region by constant reinfection from reservoir animals. Understanding the transmission routes of M. bovis in Mozambique and elsewhere is essential in order to focus public health and veterinary resources to contain bovine tuberculosis.
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