Evidence map›Paper›PMID 29346165›Full record

ReviewExercise and sport sciences reviews2018

Using Drosophila to Understand Biochemical and Behavioral Responses to Exercise.

Alyson Sujkowski, Robert Wessells

Abstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Octopamine receptors inFrontiers in molecular neuroscience · 2026
    Article
  7. Article
  8. FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila.Journal of visualized experiments : JoVE · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Progressive degeneration in a newResearch square · 2023
    Article
  15. Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  16. Article
  17. Article
  18. Regular Exercise inInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. NAD supplementation improves mitochondrial performance of cardiolipin mutants.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alyson SujkowskiDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI.
Robert Wessells

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Octopamine Mediates Benefits Of Endurance Exercise In DrosophilaR21AG055712 · NIA · WAYNE STATE UNIVERSITY · PI WESSELLS, ROBERT JOHN · 2017 to 2018
$424k
NIA NIH HHS R21 AG055712NIDDK NIH HHS P30 DK020572
6 · The paper itself

Abstract

The development of endurance exercise paradigms in Drosophila has facilitated study of genetic factors that control individual response to exercise. Recent work in Drosophila has demonstrated that activation of octopaminergic neurons is alone sufficient to confer exercise adaptations to sedentary flies. These results suggest that adrenergic activity is both necessary and sufficient to promote endurance exercise adaptations.

Indexed as

DrosophilaModels, AnimalAdaptation, PhysiologicalAnimalsExerciseFemaleHumansMaleNeuronsOctopaminePhysical Conditioning, AnimalPhysical EnduranceSex CharacteristicsOctopamine

Identifiers

PMID29346165
PMCPMC5856617

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.