Evidence map›Paper›PMID 29346160›Full record

ReviewExercise and sport sciences reviews2018

Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle With Aging.

Lee M Margolis, Donato A Rivas

Abstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  19. MicroRNAs Responding to Space Radiation.International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Lee M MargolisNutrition, Exercise, Physiology, and Sarcopenia Laboratory, U.S. Department of Agriculture Jean Mayer Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
Donato A Rivas
Jean Mayer Human Nutrition Research Center on Aging · USTufts University · US

Funding

TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
Research Training Program in Nutrition, Obesity and Metabolic DisordersT32DK062032 · NIDDK · TUFTS UNIVERSITY BOSTON · PI GREENBERG, ANDREW S · 2002 to 2016
$2.6M
Role of MicroRNAs on Age and Contraction-induced Skeletal Muscle GrowthK01AG047247 · NIA · TUFTS UNIVERSITY BOSTON · PI RIVAS, DONATO A · 2015 to 2019
$488k
NIA NIH HHS K01 AG047247NIA NIH HHS P30 AG031679NIDDK NIH HHS T32 DK062032
6 · The paper itself

Abstract

Age-induced loss of skeletal muscle mass and function, termed sarcopenia, may be the result of diminished response to anabolic stimulation. This review will explore the hypothesis that alterations in the expression of microRNA with aging contributes to reduced muscle plasticity resulting in impaired skeletal muscle adaptations to exercise-induced anabolic stimulation.

Indexed as

Resistance TrainingAdaptation, PhysiologicalAgingGene ExpressionHumansMicroRNAsMuscle ProteinsMuscle, SkeletalSarcopeniaSignal TransductionMicroRNAsMuscle Proteins

Identifiers

PMID29346160
PMCPMC5856619
OpenAlexW2790521860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.