Evidence map›Paper›PMID 29346140›Full record

ReviewCurrent opinion in pediatrics2018

Neonatal hypoglycemia: continuous glucose monitoring.

Rajesh Shah, Christopher J D McKinlay, Jane E Harding

Registry-linked trialAbstract readReview
In one paragraph

Review in Current opinion in pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04386005 (Continuous Glucose Monitoring in At-Risk Newborns), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04386005 nacompletednot on this mapstarted 2021, after this paper: background citation

Continuous Glucose Monitoring in At-Risk Newborns: A Feasibility Study

TypeinterventionalSponsorMilton S. Hershey Medical CenterRan2021 to 2026Enrolled50ConditionsNeonatal HypoglycemiaArmsContinuous Glucose Monitoring Device
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Review
  9. Dilemmas in parenteral glucose delivery and approach to glucose monitoring and interpretation in the neonate.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rajesh ShahLiggins Institute.
Christopher J D McKinlayLiggins Institute.
Jane E HardingLiggins Institute.
Counties Manukau District Health Board · NZUniversity of Auckland · NZ

Funding

Children with Hypoglycemia and their Later Development (the CHYLD Study)R01HD069622 · NICHD · UNIVERSITY OF AUCKLAND · PI HARDING, JANE · 2011 to 2015
$1.7M
NICHD NIH HHS R01 HD069622
6 · The paper itself

Abstract

purpose of reviewContinuous glucose monitoring (CGM) is increasingly used in the management of diabetes in children and adults, but there are few data regarding its use in neonates. The purpose of this article is to discuss the potential benefits and limitations of CGM in neonates. RECENT

findingsSmaller electrodes in new sensors and real-time monitoring have made CGM devices more approachable for neonatal care. CGM is well tolerated in infants including very low birth weight babies, and few if any local complications have been reported. Use of CGM in newborns may reduce the frequency of blood sampling and improve glycemic stability, with more time spent in the euglycemic range. However, CGM may also lead to more intervention, with potential adverse effects on outcomes. More information is also needed about reliability, calibration and interpretation of CGM in the neonate. SUMMARY: Although the use of CGM in neonates appears to be well tolerated, feasible and has been associated with better glycemic status, there is not yet any evidence of improved clinical outcomes. Clinical utility of CGM should be demonstrated in randomized trials prior to its introduction into regular neonatal care.

Indexed as

BiomarkersBlood GlucoseHumansHypoglycemiaInfant, NewbornIntensive Care, NeonatalMonitoring, PhysiologicBiomarkersBlood Glucose

Identifiers

PMID29346140
PMCPMC5882205
OpenAlexW2790804814

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.