Evidence map›Paper›PMID 29345996›Full record

ArticleAmerican journal of public health2018

Delays in Global Disease Outbreak Responses: Lessons from H1N1, Ebola, and Zika.

Steven J Hoffman, Sarah L Silverberg

Abstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  5. Zoonotic disease outbreaks reported under India'sThe Lancet regional health. Southeast Asia · 2025
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  9. Toward optimal disease surveillance with graph-based active learning.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Steven J HoffmanSteven J. Hoffman is with the Global Strategy Lab, Dahdaleh Institute for Global Health Research, Faculty of Health and Osgoode Hall Law School, York University, Toronto, ON, Canada, and is also with the Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA. Sarah L. Silverberg is with the Faculty of Medicine, University of Toronto, Toronto.
Sarah L SilverbergSteven J. Hoffman is with the Global Strategy Lab, Dahdaleh Institute for Global Health Research, Faculty of Health and Osgoode Hall Law School, York University, Toronto, ON, Canada, and is also with the Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Harvard University, Boston, MA. Sarah L. Silverberg is with the Faculty of Medicine, University of Toronto, Toronto.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In global disease outbreaks, there are significant time delays between the source of an outbreak and collective action. Some delay is necessary, but recent delays have been extended by insufficient surveillance capacity and time-consuming efforts to mobilize action. Three public health emergencies of international concern (PHEICs)-H1N1, Ebola, and Zika-allow us to identify and compare sources of delays and consider seven hypotheses about what influences the length of delays. These hypotheses can then motivate further research that empirically tests them. The three PHEICs suggest that deferred global mobilization is a greater source of delay than is poor surveillance capacity. These case study outbreaks support hypotheses that we see quicker responses for novel diseases when outbreaks do not coincide with holidays and when US citizens are infected. They do not support hypotheses that we see quicker responses for more severe outbreaks or those that threaten larger numbers of people. Better understanding the reason for delays can help target policy interventions and identify the kind of global institutional changes needed to reduce the spread and severity of future PHEICs.

Indexed as

Global HealthInfluenza A Virus, H1N1 SubtypeTime-to-TreatmentZika Virus InfectionCommunicable Diseases, EmergingDisease OutbreaksHemorrhagic Fever, EbolaHumansPublic Health Surveillance

Identifiers

PMID29345996
PMCPMC5803810

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.