Evidence map›Paper›PMID 29345756›Full record

ArticleJournal of the American Geriatrics Society2018

Clinical Intentions of Antibiotics Prescribed Upon Discharge to Hospice Care.

Sarah A Servid, Brie N Noble, Erik K Fromme, Jon P Furuno

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in antimicrobial stewardship: antimicrobial use during end-of-life care.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023
    Article
  8. Article
  9. The Use of Antibiotics in Hospice and Palliative Care Settings.Journal of hospice and palliative care · 2022
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sarah A ServidDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, Oregon.
Brie N NobleDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, Oregon.
Erik K FrommeHarvard Medical School, Boston, Massachusetts.
Jon P FurunoDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, Oregon.
Oregon State University · USBrigham and Women's Hospital · USOregon Health & Science University · US

Funding

OREGON CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024140 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$61.1M
Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
NCATS NIH HHS UL1 TR000128NCRR NIH HHS UL1 RR024140
6 · The paper itself

Abstract

objectivesTo better understand the clinical intentions for antibiotic prescribing upon discharge from acute care to hospice care.

designRetrospective cohort study.

settingFive hundred forty-four-bed academic, acute-care, tertiary referral hospital in Portland, Oregon.

participantsAdults (≥18) who received an outpatient prescription for antibiotics on discharge from an acute care hospital to hospice care between January 1, 2009 and December 31, 2011 (N = 149). MEASUREMENTS: We determined whether antibiotics were indicated for treatment of an active infection, palliative treatment, prophylaxis, or prescribed according to family or participant preference.

resultsAntibiotics were prescribed to 17.6% (n = 149) of individuals discharged to hospice care over the 3-year study period. Antibiotics were most frequently prescribed for pneumonia (19.5%), urinary tract infections (18.9%), and gastrointestinal tract infections (17.0%). The explicit rationale for antibiotic prescription was documented for only 72 prescriptions (45.3%). For 84 (52.8%) participants, antibiotics were used to treat an active infection in the hospital. Of prescriptions with a documented rationale, 37.5% indicated that the intent was curative, 26.4% prophylaxis, and 22.2% to suppress an infection. For 19.4% of prescriptions, participants or their family members specifically wanted to be treated with antibiotics. Only 9.7% of prescriptions specifically indicated that antibiotics were prescribed for palliative reasons.

conclusionAntibiotics were frequently prescribed for treatment of active infection in individuals discharged to hospice care. Further research is needed to document antibiotic benefits and risks and optimize medication management at the end of life.

Indexed as

DeprescriptionsAdultAnti-Bacterial AgentsBacterial InfectionsCohort StudiesDrug PrescriptionsFemaleHospice CareHumansMaleMiddle AgedOregonPatient DischargePractice Patterns, Physicians'Retrospective StudiesYoung AdultAnti-Bacterial Agentsantibioticsdischarge planninghospicetransitions of care

Identifiers

PMID29345756
PMCPMC5849491
OpenAlexW2793756479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.