ArticleeLife2018
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 98 citations in OpenAlex.
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- Donor strand complementation and calcium ion coordination drive the chaperone-free polymerization of archaeal cannulae.Nature communications · 2025Article
- A novel post-translational modification of fimbriae drives pathogenicity inbioRxiv : the preprint server for biology · 2025Article
- Tat-dependent bundling pilus of a halophilic archaeon assembles by a strand donation mechanism and facilitates biofilm formation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- 3D-printed temperature and shear stress-controlled rocker platform for enhanced biofilm incubation.Scientific reports · 2025Article
- Structures of the Escherichia coli type 1 pilus during pilus rod assembly and after assembly termination.Nature communications · 2025Article
- Bacterial adhesion strategies and countermeasures in urinary tract infection.Nature microbiology · 2025Review
- Etiological Factors and Development of a Predictive Model for Urinary Tract Infections in Cervical Cancer Patients Undergoing Intensity-Modulated Radiotherapy.Infection and drug resistance · 2025Article
- Cloning and Expression of Pigeon-DerivedGenes · 2024Article
- The assembly platform FimD is required to obtain the most stable quaternary structure of type 1 pili.Nature communications · 2024Article
- High-throughput virtual search of small molecules for controlling the mechanical stability of human CD4.The Journal of biological chemistry · 2024Article
- An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.Nature communications · 2024Article
- Functional fibrillar interfaces: Biological hair as inspiration across scales.Beilstein journal of nanotechnology · 2024Review
- Screening of antigenic epitopes related to the adhesion of the avian Escherichia coli Type 1 Fimbrial Agglutinin Domain.BMC veterinary research · 2023Article
- Endospore pili: Flexible, stiff, and sticky nanofibers.Biophysical journal · 2023Article
- FimH and Type 1 Pili Mediated Tumor Cell Cytotoxicity by UropathogenicPathogens (Basel, Switzerland) · 2023Article
- Three structural solutions for bacterial adhesion pilus stability and superelasticity.Structure (London, England : 1993) · 2023Article
- Probe-based bacterial single-cell RNA sequencing predicts toxin regulation.Nature microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 3 countries.
Caitlin N Spaulding *Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.ORCID http://orcid.org/0000-0002-7582-3816
Henry Louis Schreiber *Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.ORCID http://orcid.org/0000-0002-4501-9886
Weili Zheng *Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, United States.
Karen W DodsonCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.
Jennie E HazenCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.
Matt S ConoverCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.
Fengbin WangDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, United States.
Pontus SvenmarkerDepartment of Physics, Umeå University, Umeå, Sweden.ORCID http://orcid.org/0000-0002-1308-4923
Areli Luna-RicoDepartment of Structural Biology and Chemistry, Institut Pasteur, Biochemistry of Macromolecular Interactions Unit, Paris, France.ORCID http://orcid.org/0000-0001-7538-5441
Olivera FranceticDepartment of Structural Biology and Chemistry, Institut Pasteur, Biochemistry of Macromolecular Interactions Unit, Paris, France.ORCID http://orcid.org/0000-0002-4145-5314
Magnus AnderssonDepartment of Physics, Umeå University, Umeå, Sweden.ORCID http://orcid.org/0000-0002-9835-3263
Scott HultgrenCenter for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, United States.ORCID http://orcid.org/0000-0001-8785-564X
Edward H EgelmanDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, United States.ORCID http://orcid.org/0000-0003-4844-5212
Washington University in St. Louis · USUniversity of Virginia · USInstitut Pasteur · FRUmeå University · SE
Funding
Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Thomas P. Loughran · 1987 to 2026
$72.1Mpan-Genome of E.coli in the bladder and gut of women with recurrent UTIP50DK064540 · NIDDK · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J. · 2002 to 2017
$17.9MPATHOGENIC FIBER FORMATION IN BACTERIA: STRUCTURAL BASISR01AI048689 · NIAID · WASHINGTON UNIVERSITY · PI HULTGREN, SCOTT J. · 2001 to 2020
$7.6MCryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic ResolutionR35GM122510 · NIGMS · UNIVERSITY OF VIRGINIA · PI EDWARD H. EGELMAN · 2017 to 2026
$7.3MSTRUCTURAL STUDIES OF RECA FILAMENTSR01GM035269 · NIGMS · YALE UNIVERSITY · PI EGELMAN, EDWARD H. · 1986 to 2016
$5.2MPathogenic Fiber Formation in Bacteria: Structural BasisR37AI048689 · NIAID · WASHINGTON UNIVERSITY · PI SCOTT J. HULTGREN · 2021 to 2026
$2.9MMolecular Electron Microscopy Core Facility ImprovementsG20RR031199 · NCRR · UNIVERSITY OF VIRGINIA · PI SHUPNIK, MARGARET A · 2010 to 2010
$2.0M300 keV Liquid Helium Robotic MicroscopeS10RR025067 · NCRR · UNIVERSITY OF VIRGINIA · PI EGELMAN, EDWARD H. · 2009 to 2009
$2.0MDirect Electron Detector for a Titan Krios Robotic Electron Cryo-MicroscopeS10OD018149 · OD · UNIVERSITY OF VIRGINIA · PI EGELMAN, EDWARD H., YEAGER, MARK JAY · 2014 to 2014
$500kTlr1: Functional and Genetic Variation in Urinary Tract InfectionF32DK101171 · NIDDK · WASHINGTON UNIVERSITY · PI CONOVER, MATTHEW S. · 2014 to 2015
$113kDelineating the role of inflammation and the microbiota in uropathogenic E. coli intestinal colonizationF31DK107057 · NIDDK · WASHINGTON UNIVERSITY · PI SPAULDING, CAITLIN NICOLE · 2016 to 2017
$46kNCI NIH HHS P30 CA044579NCRR NIH HHS G20 RR031199NCRR NIH HHS S10 RR025067NIAID NIH HHS AI048689NIAID NIH HHS R01 AI048689NIAID NIH HHS R37 AI048689NIDDK NIH HHS 1F31DK107057NIDDK NIH HHS DK064540NIDDK NIH HHS DK101171-02NIDDK NIH HHS F31 DK107057NIDDK NIH HHS F32 DK101171NIDDK NIH HHS P50 DK064540NIGMS NIH HHS GM122510NIGMS NIH HHS R01 GM035269NIGMS NIH HHS R35 GM122510NIH HHS S10 OD018149
Abstract
Uropathogenic
Indexed as
Bacterial AdhesionHost-Pathogen InteractionsAdhesins, BacterialAnimalsCryoelectron MicroscopyDisease Models, AnimalEscherichia coli InfectionsFimbriae, BacterialFimbriae ProteinsMiceUrinary Tract InfectionsUropathogenic Escherichia coliAdhesins, BacterialFimbriae ProteinsfimbrillinbiophysicsChaperone-usher pathway pilicryo-EMCUP piliE. coliinfectious diseasemicrobiologymousestructural biologytype 1 piliUPECUTI
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.