ReviewDeutsches Arzteblatt international2018
Indications for the Surgical Management of Benign Goiter in Adults.
Review in Deutsches Arzteblatt international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Surgical approaches to the management of the intrathoracic goiter - A systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Pooled it
- [Frozen section in oncologic endocrine surgery].Chirurgie (Heidelberg, Germany) · 2025Pooled it
- [Update of the S2k guidelines : Surgical treatment of benign thyroid diseases].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2018Guideline
- Impact of Preoperative Calcium and Magnesium Supplementation on Quality of Life and Hypocalcemia Post-Thyroidectomy.Endocrinology, diabetes & metabolism · 2026Trial
- Impact of body mass index on neck muscle changes and postoperative outcomes in patients undergoing hemithyroidectomy: a retrospective cohort study.BMC surgery · 2025Article
- Patients undergoing thyroid surgery suffer preoperatively from poor quality of life.Journal of endocrinological investigation · 2025Article
- [Modern thyroid surgery : Efficient and safe thyroidectomy technique].Chirurgie (Heidelberg, Germany) · 2024Review
- [Local ablative procedures for treatment of thyroid nodules].Chirurgie (Heidelberg, Germany) · 2024Article
- Redo Thyroidectomy: Updated Insights.Journal of clinical medicine · 2024Review
- Intraoperative thyroid frozen section: indications, results and consequences.Gland surgery · 2024Article
- Observational
- [69/f-Increased neck circumference, stridor and dyspnea when lying : Preparation for the medical specialist examination: part 32].Chirurgie (Heidelberg, Germany) · 2023Article
- [Hereditary medullary thyroid cancer].Chirurgie (Heidelberg, Germany) · 2023Review
- Case report: Preliminary study on the diagnosis and treatment of respiratory distress in patients with giant nodular goiter complicated with severe COVID-19.Frontiers in medicine · 2023Article
- Indications and complications for surgical management of thyroid diseases: A single center experience.Annals of medicine and surgery (2012) · 2022Article
- Impact of thyroidectomy on quality of life in benign goitres: results from a prospective cohort study.Langenbeck's archives of surgery · 2022Article
- Shear Wave Elastography and Thyroid Imaging Reporting and Data System (TIRADS) for the Risk Stratification of Thyroid Nodules-Results of a Prospective Study.Diagnostics (Basel, Switzerland) · 2022Article
- Ultrasound Imaging of Cervical Anatomic Variants.Current medical imaging · 2021Article
- Shared Decision Making for Radioiodine Therapy and the Actual Pattern of Care in Intermediate-Risk Differentiated Thyroid Carcinoma.Frontiers in nuclear medicine · 2021Review
- [The thyroid gland in old age : Physiology and pathology].Wiener medizinische Wochenschrift (1946) · 2020Article
Corrections and comments
- Commented on by
- Erratum issuedErratum.2018
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThyroidectomy is still three to six times more common in Germany than in the USA, Great Britain, and the Scandinavian countries. Thus, the question is often asked whether thyroidectomy in Germany is being performed for the correct indications.
methodsThis review is based on studies and guidelines containing information on the indications for surgery in benign goiter and Graves' disease; these publications were retrieved by a systematic literature search in the Medline and Cochrane Library databases (1990-2016). The indications recommended here were determined by vote by the German Society for General and Visceral Surgery (Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie, DGAV).
resultsOn the basis of the available evidence (levels 2-4), and in the absence of prospective studies, the indications for surgery in goiter include a well-founded suspicion of malignancy, local compressive symptoms, and, rarely, cosmesis. In hyperthyroid goiter and Graves' disease, surgery is a potential alternative to radio - iodine therapy, particularly if the volume of the thyroid gland exceeds 80 mL, in patients with advanced or active orbitopathy, and in female patients who are, or plan to be, pregnant. Large, asymptomatic, euthyroid nodular goiter without any suspicion of malignancy and scintigraphically "cold" nodules without any other evidence of malignancy are not indications for surgery. Thyroid operations of higher levels of difficulty (e.g., recurrent goiter, retrosternal extension, Graves' disease) should be carried out in institutions with special expertise in thyroid surgery.
conclusionThe decision to operate should be made on an interdisciplinary basis and in conformity with the relevant guidelines after all of the appropriate diagnostic studies have been performed. The radicality of any proposed surgical procedure should be weighed against its potential complications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.