Evidence map›Paper›PMID 29345190›Full record

ArticleNanomedicine (London, England)2018

Magnetoelectric nanoparticles for delivery of antitumor peptides into glioblastoma cells by magnetic fields.

Tiffanie S Stewart, Abhignyan Nagesetti, Rakesh Guduru, Ping Liang, Emmanuel Stimphil, Ali Hadjikhani, Luis Salgueiro, Jeffrey Horstmyer, Renzhi Cai, Andrew Schally and 1 more

Open access · greenAbstract read
In one paragraph

Article in Nanomedicine (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 59 citations in OpenAlex.

  1. Review
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  4. Article
  5. Theoretical Modeling of the Interactions of CoFeCurrent medicinal chemistry · 2025
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  10. Review
  11. Article
  12. Article
  13. Synthesis and Functional Characterization of CoNanomaterials (Basel, Switzerland) · 2023
    Article
  14. Review
  15. Biocompatible, Multi-Mode, Fluorescent,Pharmaceuticals (Basel, Switzerland) · 2022
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tiffanie S StewartCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Abhignyan NagesettiCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Rakesh GuduruCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Ping LiangCellular Nanomed, Coral Springs, FL, USA.
Emmanuel StimphilCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Ali HadjikhaniCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Luis SalgueiroVeterans Affairs Medical Center, University of Miami School of Medicine, Miami, FL, USA.
Jeffrey HorstmyerBrain Center, Miami, FL, USA.
Renzhi CaiVeterans Affairs Medical Center, University of Miami School of Medicine, Miami, FL, USA.
Andrew SchallyVeterans Affairs Medical Center, University of Miami School of Medicine, Miami, FL, USA.
Sakhrat KhizroevCenter for Personalized Nanomedicine, Florida International University, Miami, FL, USA.
Florida International University · USUniversity of Miami · US

Funding

Cocaine in the Neuropathogenesis of HIV infection: Role of HDAC2R01DA034547 · NIDA · FLORIDA INTERNATIONAL UNIVERSITY · PI NAIR, MADHAVAN P. · 2013 to 2018
$1.8M
NIDA NIH HHS R01 DA034547
6 · The paper itself

Abstract

aimWe studied externally controlled anticancer effects of binding tumor growth inhibiting synthetic peptides to magnetoelectric nanoparticles (MENs) on treatment of glioblastomas.

methodsHydrothermally synthesized 30-nm MENs had the core-shell composition of CoFe

resultsThe studies demonstrated externally controlled high-efficacy binding of MIA690 to MENs, targeted specificity to glioblastoma cells and on-demand release of the peptide by application of d.c. and a.c. magnetic fields, respectively.

conclusionThe results support the use of MENs as an effective drug delivery carrier for growth hormone-releasing hormone antagonists in the treatment of human glioblastomas.

Indexed as

Antineoplastic AgentsBarium CompoundsBrainBrain NeoplasmsCell Line, TumorCell SurvivalCobaltDrug CarriersDrug LiberationEndothelial CellsFerric CompoundsGlioblastomaGrowth HormoneHormone AntagonistsHumansMagnetic FieldsAntineoplastic AgentsBarium Compoundsbarium titanate(IV)Cobaltcobalt ferriteDrug CarriersFerric CompoundsGrowth HormoneHormone AntagonistsMagnetite NanoparticlesPeptidesTitaniumcancer/oncologygene/drug deliverynanoparticles

Identifiers

PMID29345190
PMCPMC5810849
OpenAlexW2793791746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.