ArticleActa obstetricia et gynecologica Scandinavica2018
Preeclampsia and scleroderma: a prospective nationwide analysis.
Article in Acta obstetricia et gynecologica Scandinavica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Is a History of Pre-eclampsia Before Systemic Sclerosis Onset a Risk Factor for Vascular Phenotype in Women With Systemic Sclerosis?
Validation of the French Translation of a Self-questionnaire Looking for a History of Pre-eclampsia of More Than 5 Years in Women Who Have Already Had a Pregnancy of More Than 6 Months With Childbirth at Brest University Hospital.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Pregnancy complications and autoimmune diseases in women: systematic review and meta-analysis.BMC medicine · 2024Pooled it
- The Immunopathology of Preeclampsia.Biomedicines · 2026Review
- Defective Trophoblast Differentiation, Endothelial Dysfunction, and Immune Dysregulation in Preeclampsia Coalesce on a Placental VGLL3-Centered Gene Network.Circulation · 2026Article
- VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia.bioRxiv : the preprint server for biology · 2025Article
- History of pre-eclampsia does not appear to be a risk factor for vascular phenotype in women with systemic sclerosis.RMD open · 2024Observational
- Hypertensive diseases of pregnancy and risk of breast cancer in the Black Women's Health Study.Breast cancer research and treatment · 2022Article
- Increased Rates of Obstetric Complications Prior to Systemic Sclerosis Diagnosis.Arthritis care & research · 2022Article
- Nature's endless wonder: unexpected motherhood after pediatric allogeneic stem cell transplantation and severe late effects.Wiener klinische Wochenschrift · 2020Article
- Feto-Maternal Microchimerism: The Pre-eclampsia Conundrum.Frontiers in immunology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
introductionIn a preliminary case-control study, women with scleroderma more frequently reported having had hypertensive complications during pregnancy compared with healthy women. MATERIAL AND
methodsTo prospectively investigate this possible association, we conducted a nation-wide cohort analysis of a major hypertensive complication during pregnancy, namely preeclampsia, and later scleroderma. Analyses were based on Danish register-based birth and hospital contact data on preeclampsia and scleroderma. We followed 778,758 women from time of giving birth between 1978 and 2010 to end of follow-up, emigration, death, or scleroderma diagnosis, whichever occurred first. The association was evaluated by incidence rate ratios, obtained in Poisson regression models.
resultsWe report that preeclampsia is associated with a 69% significantly increased risk of later developing scleroderma.
conclusionsThough these findings do not impact clinical care directly, the association of preeclampsia with scleroderma underscores the significant relation of preeclampsia and other adverse pregnancy outcomes with later disease in women and should be included in patient counseling and education.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.