ArticleJournal of anatomy2018
Systemic patterns of trabecular bone across the human and chimpanzee skeleton.
Article in Journal of anatomy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 61 citations in OpenAlex.
- Variation in trabecular bone microarchitecture across rhesus macaque (Macaca mulatta) load-bearing joints.Journal of anatomy · 2026Article
- Growing together: Developmental integration and modularity in the human talus-calcaneus complex.Journal of anatomy · 2026Article
- SwartkransProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Locomotor signals in the trabecular structure of the hominoid clavicle.Journal of anatomy · 2025Article
- Trabecular Architecture of the Proximal Tibia in Extant Hominids.American journal of biological anthropology · 2025Article
- Functional morphology of trabecular system in human proximal femur: a perspective from P45 sectional plastination and 3D reconstruction finite element analysis.Journal of orthopaedic surgery and research · 2025Article
- The Ontogeny of the Human Calcaneus: Insights From Morphological and Trabecular Changes During Postnatal Growth.American journal of biological anthropology · 2025Article
- The Virtual Database of the Documented Human Osteological Collection (DHOC) of the Certosa Cemetery of Bologna (Italy, 19th-20th Century).American journal of biological anthropology · 2025Article
- Restructuring of Femoral Cortical Bone During Growth and Locomotor Development of Wild Chimpanzees (Pan troglodytes verus).American journal of biological anthropology · 2025Article
- A new biomechanical model of the mammal jaw based on load path analysis.The Journal of experimental biology · 2024Article
- Identification of functionally related adaptations in the trabecular network of the proximal femur and tibia of a bipedally trained Japanese macaque.Anthropological science : journal of the Anthropological Society of Nippon = Jinruigaku zasshi · 2024Article
- Serum vitamin D in sanctuary chimpanzees (Pan troglodytes) in range countries: A pilot study.Veterinary medicine and science · 2023Article
- A computational framework for canonical holistic morphometric analysis of trabecular bone.Scientific reports · 2022Article
- Effects of reduced mobility on trabecular bone density in captive big cats.Royal Society open science · 2022Article
- Variation, mosaicism and degeneracy in the hominin foot.Evolutionary human sciences · 2022Review
- Novel strategies for the characterization of cancellous bone morphology: Virtual isolation and analysis.American journal of physical anthropology · 2021Article
- Cortical and trabecular bone structure of the hominoid capitate.Journal of anatomy · 2021Article
- Musculoskeletal modelling of the Nile crocodile (Crocodylus niloticus) hindlimb: Effects of limb posture on leverage during terrestrial locomotion.Journal of anatomy · 2021Article
- Locomotory behaviour of early tetrapods from Blue Beach, Nova Scotia, revealed by novel microanatomical analysis.Royal Society open science · 2021Article
- Mineralized Cartilage and Bone-Like Tissues in Chondrichthyans Offer Potential Insights Into the Evolution and Development of Mineralized Tissues in the Vertebrate Endoskeleton.Frontiers in genetics · 2021Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspects of trabecular bone architecture are thought to reflect regional loading of the skeleton, and thus differ between primate taxa with different locomotor and postural modes. However, there are several systemic factors that affect bone structure that could contribute to, or be the primary factor determining, interspecific differences in bone structure. These systemic factors include differences in genetic regulation, sensitivity to loading, hormone levels, diet, and activity levels. Improved understanding of inter-/intraspecific variability, and variability across the skeleton of an individual, is required to interpret properly potential functional signals present within trabecular structure. Using a whole-region method of analysis, we investigated trabecular structure throughout the skeleton of humans and chimpanzees. Trabecular bone volume fraction (BV/TV), degree of anisotropy (DA) and trabecular thickness (Tb.Th) were quantified from high resolution micro-computed tomographic scans of the humeral and femoral head, third metacarpal and third metatarsal head, distal tibia, talus and first thoracic vertebra. We found that BV/TV is, in most anatomical sites, significantly higher in chimpanzees than in humans, suggesting a systemic difference in trabecular structure unrelated to local loading regime. Differences in BV/TV between the forelimb and hindlimb did not clearly reflect differences in locomotor loading in the study taxa. There were no clear systemic differences between the taxa in DA and, as such, this parameter might reflect function and relate to differences in joint loading. This systemic approach reveals both the pattern of variability across the skeleton and between taxa, and helps identify those features of trabecular structure that may relate to joint function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.