ArticleIndian journal of pediatrics2018
Development of a Prognostic Prediction Model to Determine Severe Dengue in Children.
Article in Indian journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 4 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Prognostic Models in Patients with Dengue: A Systematic Review.The American journal of tropical medicine and hygiene · 2025Pooled it
- Clinical signs and symptoms associated with WHO severe dengue classification: a systematic review and meta-analysis.Emerging microbes & infections · 2021Pooled it
- Clinical predictors of severe dengue: a systematic review and meta-analysis.Infectious diseases of poverty · 2021Pooled it
- Risk predictors of progression to severe disease during the febrile phase of dengue: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2021Pooled it
- Correlation of Serum Lipid Profile with Severity and Clinical Outcomes in Children with Dengue Fever - A Cross-Sectional Study.Indian journal of pediatrics · 2025Article
- Early Dengue Prediction in Bangladesh: A Comparative Study With Feature Analysis, Explainable Artificial Intelligence, and Model Optimization.Journal of tropical medicine · 2025Article
- Severe COVID-19 multisystem inflammatory syndrome versus severe dengue in children from Indonesia: a cross-sectional study.International journal of emergency medicine · 2024Article
- Article
- Outcomes among children and adults at risk of severe dengue in Sri Lanka: Opportunity for outpatient case management in countries with high disease burden.PLoS neglected tropical diseases · 2021Article
- Risk Factors and Predictors of Severe Dengue in Saudi Population in Jeddah, Western Saudi Arabia: A Retrospective Study.The American journal of tropical medicine and hygiene · 2020Article
- Severe Dengue: Developing a Universally Applicable Simple Prediction Model.Indian journal of pediatrics · 2018Article
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Abstract
objectiveTo develop a prognostic prediction model using the seven warning signs highlighted by WHO revised Dengue fever classification 2009 to determine severe dengue in children.
methodsIn this prospective analytical study conducted in a tertiary care centre, consecutive sampling of all children aged 1mo to 12y admitted with serologically confirmed Dengue was done from May 2015 through August 2016. After excluding 27 patients with co-infections and co-morbidities, 359 patients were followed up daily to assess clinical and laboratory progression till discharge/ death. Independent predictors were abdominal pain or tenderness, persistent vomiting, lethargy, mucosal bleed, clinical fluid accumulation, hepatomegaly >2 cm and rising hematocrit concurrent with platelet count <100 × 10
resultsAmong 359 children, 93 progressed to severe dengue. In univariate analysis, significant predictors were clinical fluid accumulation (OR 4.773, p = 0.000, 95%CI 2.511-9.075), persistent vomiting (OR 1.944, p = 0.010, 95%CI 1.170-3.225), mucosal bleed (OR 2.045, p = 0.019, 95%CI 1.127-3.711) and hematocrit ≥0.40 concurrent with platelet count <100 × 10
conclusionsAmong seven WHO warning signs, predictors of severe dengue as suggested by the present multivariable prediction model include clinical fluid accumulation, persistent vomiting and hematocrit ≥0.40 concurrent with platelet count <100 × 10
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