Evidence map›Paper›PMID 29344826›Full record

ArticleMarine biotechnology (New York, N.Y.)2018

Phytochemical Analysis and Evaluation of the Antioxidant, Anti-Inflammatory, and Antinociceptive Potential of Phlorotannin-Rich Fractions from Three Mediterranean Brown Seaweeds.

Amal Abdelhamid, Meriem Jouini, Haifa Bel Haj Amor, Zeineb Mzoughi, Mehdi Dridi, Rafik Ben Said, Abderrahman Bouraoui

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  7. Article
  8. Anti-Melanogenic Activities ofFoods (Basel, Switzerland) · 2024
    Article
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  10. Article
  11. Article
  12. Article
  13. Review
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  18. Antifungal Activity of the Extract of a Macroalgae,Plants (Basel, Switzerland) · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amal AbdelhamidLaboratory of Chemical, Galenic and Pharmacological Development of Drugs, Faculty of Pharmacy of Monastir, University of Monastir, 5000, Monastir, Tunisia. amal.abdelhamid87@gmail.com.ORCID http://orcid.org/0000-0003-0045-9076
Meriem JouiniLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity, Medicinal Chemistry and Natural Products Team, Faculty of Sciences of Monastir, University of Monastir, 5019, Monastir, Tunisia.
Haifa Bel Haj AmorLaboratory of Chemical, Galenic and Pharmacological Development of Drugs, Faculty of Pharmacy of Monastir, University of Monastir, 5000, Monastir, Tunisia.
Zeineb MzoughiLaboratory of Interfaces and Advanced Materials, Faculty of Sciences of Monastir, University of Monastir, 5000, Monastir, Tunisia.
Mehdi DridiLaboratory of Chemical, Galenic and Pharmacological Development of Drugs, Faculty of Pharmacy of Monastir, University of Monastir, 5000, Monastir, Tunisia.
Rafik Ben SaidNational Institute of Marine Sciences and Technologies, Salambôo, Tunis, Tunisia.
Abderrahman BouraouiLaboratory of Chemical, Galenic and Pharmacological Development of Drugs, Faculty of Pharmacy of Monastir, University of Monastir, 5000, Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phlorotannins, phenolic compounds produced exclusively by seaweeds, have been reported to possess various pharmacological properties. However, there have been few works on these compounds from Mediterranean seaweeds. In this study, we investigated the phytochemical analysis and pharmacological potential of phlorotannin-rich fractions from three brown seaweeds collected along the Tunisia coast: Cystoseira sedoides (PHT-SED), Cladostephus spongeosis (PHT-CLAD), and Padina pavonica (PHT-PAD). Phytochemical determinations showed considerable differences in total phenolic content (TPC) and phlorotannin content (PHT). The highest TPC level (26.45 mg PGE/g dry material (Dm)) and PHT level (873.14 μg PGE/g Dm) were observed in C. sedoides. The antioxidant properties of these three fractions assessed by three different methods indicated that C. sedoides displayed the highest total antioxidant activity among the three species (71.30 mg GAE/g Dm), as well as the free radical scavenging activity with the lowest IC

Indexed as

AnalgesicsAnimalsAnti-Inflammatory AgentsAntioxidantsEdemaFemaleLipid PeroxidationLiverMaleMicePhaeophyceaeRats, WistarTanninsTramadolAnalgesicsAnti-Inflammatory AgentsAntioxidantsTanninsTramadolAnti-inflammatory activityAntinociceptive activityBrown seaweedPhlorotanninsPhytochemicalRadical scavenging activity

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.