Evidence map›Paper›PMID 29344677›Full record

SynthesisEuropean journal of nutrition2019

Is vitamin D deficiency a public health concern for low middle income countries? A systematic literature review.

Kevin D Cashman, Tony Sheehy, Colette M O'Neill

Registry-linked trialAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04030182 (Vitamin D Deficit in Women With Uterine Fibroids), which is not on this map. Cited by 52 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04030182 completednot on this map

Vitamin D Deficit in Women With Uterine Fibroids

TypeobservationalSponsorInstituto Mexicano del Seguro SocialRan2019 to 2021Enrolled127ConditionsLeiomyoma, Vitamin D Deficiency, Fibroid UterusArmsLevel of Vitamin D
3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Trial
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  9. Article
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  13. Vitamin D and Intrauterine Growth Restriction (IUGR).International journal of molecular sciences · 2025
    Review
  14. Article
  15. FokI Polymorphism of theNutrients · 2025
    Article
  16. Article
  17. Article
  18. Optimisation of vitamin D status in global populations.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin D CashmanCork Centre for Vitamin D and Nutrition Research, University College Cork, Cork, Ireland. k.cashman@ucc.ie.ORCID http://orcid.org/0000-0002-8185-1039
Tony SheehySchool of Food and Nutritional Sciences, University College Cork, Cork, Ireland.
Colette M O'NeillCork Centre for Vitamin D and Nutrition Research, University College Cork, Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVitamin D deficiency has been receiving increasing attention as a potential public health concern in low and lower-middle income countries (LMICs), of which there are currently 83. We aimed to conduct a comprehensive systematic literature review (SLR) of available data on vitamin D status and prevalence of vitamin D deficiency in all 83 LMICs.

methodsWe followed the general methodology for SLRs in the area of serum 25-hydroxyvitamin D. Highest priority was placed on identifying relevant population-based studies, followed by cross-sectional studies, and to a lesser extent case-control studies. We adopted the public health convention that a prevalence of vitamin D deficiency (serum 25-hydroxyvitamin D < 25/30 nmol/L) at > 20% in the entire population and/or at-risk population subgroups (infants, children, women of child-bearing age, pregnancy) constitutes a public health issue that may warrant intervention.

resultsOur SLR revealed that of the 83 LMICs, 65% (n = 54 countries) had no published studies with vitamin D data suitable for inclusion. Using data from the remaining third, a number of LMICs had evidence of excess burden of vitamin D deficiency in one or more population subgroup(s) using the above convention (Afghanistan, Pakistan, India, Tunisia and Mongolia) as well as possibly other LMICs, albeit with much more limited data. Several LMICs had no evidence of excess burden.

conclusionVitamin D deficiency is a public health issue in some, but certainly not all, LMICs. There is a clear need for targeting public health strategies for prevention of vitamin D deficiency in those LMICs with excess burden.

Indexed as

Developing CountriesHumansPublic HealthVitamin D DeficiencyFAO food balance sheetsFood fortificationLow and lower-middle income countriesSerum 25(OH)DSystematic reviewVitamin D deficiency

Identifiers

PMID29344677

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.