Evidence map›Paper›PMID 29344586›Full record

ArticleBlood advances2018

Systemic multilineage engraftment in mice after in utero transplantation with human hematopoietic stem cells.

Russell G Witt, Emily M Kreger, Laura B Buckman, Patriss W Moradi, Phong T Ho, S Christopher Derderian, Perry Tsai, Chris Baker, Nathaniel Schramm, Rachel Cleary and 2 more

Abstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The making of cells and organs in xenogeneic animal bioreactor.Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Russell G WittEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.
Emily M KregerEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.
Laura B BuckmanDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Patriss W MoradiEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.
Phong T HoDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
S Christopher DerderianEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.
Perry TsaiDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Chris BakerEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.
Nathaniel SchrammDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Rachel ClearyDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
J Victor GarciaDivision of Infectious Diseases, Center for AIDS Research, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.
Tippi C MacKenzieEli and Edythe Broad Center of Regeneration Medicine, San Francisco, CA.

Funding

INFECTIOUS DISEASE PATHOGENESIS TRAININGT32AI007151 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JULIANO, JONATHAN J · 1985 to 2024
$5.5M
Vaginal/Rectal HIV Transmission ModelR01AI073146 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI GARCIA-MARTINEZ, J. VICTOR · 2007 to 2016
$4.8M
Role of Myeloid Cells in HIV latency in the Periphery and the CNSR01MH108179 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GARCIA-MARTINEZ, J. VICTOR · 2015 to 2019
$2.7M
Plug & Purge: In Vivo Targeting of Active HIV Reservoirs That Persist Despite ARTR01AI111899 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI GARCIA-MARTINEZ, J. VICTOR · 2014 to 2018
$2.5M
NIAID NIH HHS R01 AI073146NIAID NIH HHS R01 AI111899NIAID NIH HHS T32 AI007151NIMH NIH HHS R01 MH108179
6 · The paper itself

Abstract

IUHCT of human cord blood-derived CD34

Indexed as

Cell LineageGraft SurvivalAnimalsAntibodiesCell DifferentiationChimerismFetal BloodFetal DiseasesHematopoietic Stem Cell TransplantationHumansMiceMice, SCIDModels, AnimalProto-Oncogene Proteins c-kitTransplantation, HeterologousAntibodiesProto-Oncogene Proteins c-kit

Identifiers

PMID29344586
PMCPMC5761626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.