ArticleBlood advances2018
Heterozygous
Open access · goldAbstract read
In one paragraph
Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 59 citations in OpenAlex.
- Trial
- Genomic and computational analysis of variants in telomere regulatory genes in subjects with bone marrow failure.European journal of human genetics : EJHG · 2026Article
- Reconceptualizing Aplastic Anemia-Seed, Worm, Soil.Journal of clinical laboratory analysis · 2026Review
- Subclinical Telomere Biology Disorder in Cancer Patients Heterozygous for the RTEL1 R1264H Founder Variant.American journal of medical genetics. Part A · 2026Article
- Clonal Signatures of Telomere Biology Disorders.Current hematologic malignancy reports · 2026Review
- Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.Nature genetics · 2025Article
- Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1.Nucleic acids research · 2025Article
- Emergence and Cytogenetic Clonal Evolution of Chromosome 7 Abnormalities in Myeloid Malignancies: Investigating the Role of Telomere Dysfunction.International journal of molecular sciences · 2025Article
- Germline variants in acquired aplastic anemia: current knowledge and future perspectives.Haematologica · 2024Review
- Discovery of a Novel Shared Variant AmongInternational journal of genomics · 2024Article
- A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells.Open biology · 2024Article
- Article
- Telomeres: Dysfunction, Maintenance, Aging and Cancer.Aging and disease · 2023Review
- Unraveling DNA Repair Processes In Vivo: Insights from Zebrafish Studies.International journal of molecular sciences · 2023Review
- Regulator of telomere elongation helicase 1 gene and its association with malignancy.Cancer reports (Hoboken, N.J.) · 2023Review
- Germline landscape ofFrontiers in oncology · 2023Article
- Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency.European journal of immunology · 2022Article
- Impact of diagnostic genetics on remission MRD and transplantation outcomes in older patients with AML.Blood · 2022Article
- Network inference with Granger causality ensembles on single-cell transcriptomics.Cell reports · 2022Article
- Hypoplastic myelodysplastic syndrome and acquired aplastic anemia: Immune‑mediated bone marrow failure syndromes (Review).International journal of oncology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 6 institutions in 4 countries.
Judith C W MarshDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Fernanda Gutierrez-RodriguesHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
James CooperHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Jie JiangDepartment of Haematological Medicine, Cancer Studies Division, Rayne Institute, King's College, London, United Kingdom.
Shreyans GandhiDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Sachiko KajigayaHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Xingmin FengHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Maria Del Pilar F IbanezHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Flávia S DonairesDepartment of Internal Medicine, University of Sao Paulo at Ribeirao Preto School of Medicine, Ribeirao Preto, Brazil.
João P Lopes da SilvaDepartment of Internal Medicine, University of Sao Paulo at Ribeirao Preto School of Medicine, Ribeirao Preto, Brazil.
Zejuan LiUniversity of Chicago Genetic Services Laboratory, Chicago, IL; and.
Soma DasUniversity of Chicago Genetic Services Laboratory, Chicago, IL; and.
Maria IbanezDepartment of Haematological Medicine, Cancer Studies Division, Rayne Institute, King's College, London, United Kingdom.
Alexander E SmithDepartment of Haematological Medicine, Cancer Studies Division, Rayne Institute, King's College, London, United Kingdom.
Nicholas LeaDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Steven BestDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Robin IrelandDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Austin G KulasekararajDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Donal P McLornanDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Anthony PagliucaDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
Isabelle CallebautInstitut de Mineralogie et de Physique des Milieux Condenses, Sorbonne University, Unités Mixtes de Recherche, Centre National de la Recherche Scientifique 7590, Paris, France.
Neal S YoungHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Rodrigo T CaladoDepartment of Internal Medicine, University of Sao Paulo at Ribeirao Preto School of Medicine, Ribeirao Preto, Brazil.
Danielle M TownsleyHematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Ghulam J MuftiDepartment of Haematological Medicine, King's College Hospital, London, United Kingdom.
King's College Hospital · GBNational Heart Lung and Blood Institute · USKing's College London · GBUniversidade de São Paulo · BRUniversity of Chicago · USSorbonne Université · FR
Funding
Telomeres DiseasesZIAHL006089 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI YOUNG, NEAL S · 2010 to 2025
$26.2MAbstract
Biallelic germline mutations in
Indexed as
AdultAnemia, AplasticBone Marrow DiseasesBone Marrow Failure DisordersDNA HelicasesFemaleGenetic VariationGerm-Line MutationHemoglobinuria, ParoxysmalHeterozygoteHumansLeukemia, MyeloidMaleMiddle AgedMutationTelomereDNA HelicasesRTEL1 protein, human
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.