Evidence map›Paper›PMID 29344445›Full record

ArticleAnesthesiology and pain medicine2017

Comparing Postoperative Complications and Inflammatory Markers Using Total Intravenous Anesthesia Versus Volatile Gas Anesthesia for Pancreatic Cancer Surgery.

Jose M Soliz, Ifeyinwa C Ifeanyi, Mathew H Katz, Jonathan Wilks, Juan P Cata, Thomas McHugh, Jason B Fleming, Lei Feng, Thomas Rahlfs, Morgan Bruno and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Anesthesiology and pain medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jose M SolizDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Ifeyinwa C IfeanyiDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Mathew H KatzDepartment of Surgical Oncology, Houston, TX, USA.
Jonathan WilksDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Juan P CataDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Thomas McHughDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Jason B FlemingDepartment of Surgical Oncology, Houston, TX, USA.
Lei FengDepartment of Biostatistics, Houston, TX, USA.
Thomas RahlfsDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Morgan BrunoDepartment of Surgical Oncology, Houston, TX, USA.
Vijaya GottumukkalaDepartment of Anesthesiology and Perioperative Medicine, Houston, TX, USA.
Anesthesiology and Surgical Oncology Research Group · USCancer Research And Biostatistics · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

objectivesThe objective of this study is to evaluate postoperative complications and inflammatory profiles when using a total intravenous anesthesia (TIVA) or volatile gas-opioid (VO) based anesthesia in patients undergoing pancreatic cancer surgery.

methodsDesign, retrospective propensity score matched cohort; Setting, major academic cancer hospital; Patients, all patients who had pancreatic surgery between November 2011 and August 2014 were retrospectively reviewed. Propensity score matched patient pairs were formed. A total of 134 patients were included for analysis with 67 matched pairs; Interventions, Patients were categorized according to type of anesthetic used (TIVA or VO). Patients in the TIVA group received preoperative celecoxib, tramadol, and pregabalin in addition to intraoperative TIVA with propofol, lidocaine, ketamine, and dexmedetomidine. The VO-group received a volatile-opioid based anesthetic; Measurements, demographic, perioperative clinical data, platelet lymphocyte ratios, and neutrophil lymphocyte ratios were collected. Complications were graded and collected prospectively and later reviewed retrospectively.

resultsPatients receiving TIVA were more likely to have no complication or a lower grade complication than the VO-group (P = 0.014). There were no differences in LOS or postoperative inflammatory profiles noted between the TIVA and VO groups.

conclusionsIn this retrospective matched analysis of patients undergoing pancreatic cancer surgery, TIVA was associated with lower grade postoperative complications. Length of hospital stay (LOS) and postoperative inflammatory profiles were not significantly different.

Indexed as

AnesthesiaCancerComplicationsPancreas SurgeryTIVAVolatile Anesthesia

Identifiers

PMID29344445
PMCPMC5750426
OpenAlexW2750166836

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.