Evidence map›Paper›PMID 29344311›Full record

ArticleTheranostics2018

Gilz-Activin A as a Novel Signaling Axis Orchestrating Mesenchymal Stem Cell and Th17 Cell Interplay.

Patricia Luz-Crawford, Gabriel Espinosa-Carrasco, Natacha Ipseiz, Rafael Contreras, Gautier Tejedor, Daniel A Medina, Ana-Maria Vega-Letter, Devi Ngo, Eric F Morand, Jérôme Pène and 3 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Mesenchymal Stem Cell Engineering.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  5. Combination treatment with interferon-γ may be a potential strategy to improve the efficacy of cytotherapy for rheumatoid arthritis: A network meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Review
  6. Review
  7. Article
  8. Transfer of mesenchymal stem cell mitochondria to CD4Stem cell research & therapy · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 5 countries.

Patricia Luz-CrawfordIRMB, INSERM, Université Montpellier, Montpellier, France.
Gabriel Espinosa-CarrascoIRMB, INSERM, Université Montpellier, Montpellier, France.
Natacha IpseizCardiff University School of Medicine, United Kingdom.
Rafael ContrerasIRMB, INSERM, Université Montpellier, Montpellier, France.
Gautier TejedorIRMB, INSERM, Université Montpellier, Montpellier, France.
Daniel A MedinaDepartment of Chemical and Bioprocess Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile.
Ana-Maria Vega-LetterClinica Alemana Universidad del Desarrollo, Santiago, Chile.
Devi NgoSchool of Clinical Sciences, Monash University, Melbourne, Australia.
Eric F MorandSchool of Clinical Sciences, Monash University, Melbourne, Australia.
Jérôme PèneIRMB, INSERM, Université Montpellier, Montpellier, France.
Javier HernandezIRMB, INSERM, Université Montpellier, Montpellier, France.
Christian JorgensenIRMB, INSERM, Université Montpellier, Montpellier, France.
Farida DjouadIRMB, INSERM, Université Montpellier, Montpellier, France.
Inserm · FRUniversité de Montpellier · FRMonash University · AUCardiff University · GBHôpital Lapeyronie · FRPontificia Universidad Católica de Chile · CLUniversidad del Desarrollo · CLUniversidad de Los Andes · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSC) are highly immunosuppressive cells able to reduce chronic inflammation through the active release of mediators. Recently, we showed that glucocorticoid-induced leucine zipper (Gilz) expression by MSC is involved in their therapeutic effect by promoting the generation of regulatory T cells. However, the mechanisms underlying this pivotal role of Gilz remain elusive.

Indexed as

Cell DifferentiationActivinsAnimalsCells, CulturedCross-PrimingInterferon-gammaInterleukin-10Mesenchymal Stem CellsMiceMice, Inbred BALB CMice, Inbred C57BLMice, Inbred DBANitric Oxide Synthase Type IISmad ProteinsTh17 CellsTranscription Factorsactivin AActivinsDsip1 protein, mouseInterferon-gammaInterleukin-10Nitric Oxide Synthase Type IISmad ProteinsTranscription FactorsTumor Necrosis Factor-alphaActivin AGilzImmunosuppression.Mesenchymal Stem CellsTh17 cells

Identifiers

PMID29344311
PMCPMC5771098
OpenAlexW2781019679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.