Evidence map›Paper›PMID 29344300›Full record

ArticleTheranostics2018

General Anesthesia Inhibits the Activity of the "Glymphatic System".

Clement Gakuba, Thomas Gaberel, Suzanne Goursaud, Jennifer Bourges, Camille Di Palma, Aurélien Quenault, Sara Martinez de Lizarrondo, Denis Vivien, Maxime Gauberti

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it, 191 citations in OpenAlex.

  1. Pooled it
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  16. Sleep Patterns and Human Brain Health.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025
    Review
  17. Article
  18. Cerebral small vessel disease: The impact of glymphopathy and sleep disorders.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
  19. Article
  20. Review

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Clement GakubaNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Thomas GaberelNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Suzanne GoursaudNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Jennifer BourgesNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Camille Di PalmaNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Aurélien QuenaultNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Sara Martinez de LizarrondoNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Denis VivienNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Maxime GaubertiNormandie Univ, UNICAEN, INSERM, INSERM UMR-S U1237, "Physiopathology and Imaging of Neurological Disorders" PhIND, 14000 Caen, France.
Inserm · FRCentre Hospitalier Universitaire de Caen · FRUniversité de Caen Normandie · FRNormandie Université · FRPhysiopathologie et imagerie des troubles neurologiques

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anesthesia, GeneralAnesthetics, InhalationAnimalsContrast MediaFluorescent DyesGlymphatic SystemMagnetic Resonance ImagingMaleMiceSpectroscopy, Near-InfraredAnesthetics, InhalationContrast MediaFluorescent DyesAlzheimeranesthesiachoroid plexus.glymphatic systemmagnetic resonance imaging

Identifiers

PMID29344300
PMCPMC5771087
OpenAlexW2769041798

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.