Evidence map›Paper›PMID 29344255›Full record

ArticleOncology letters2017

Plasma olfactomedin 4 level in peripheral blood and its association with clinical features of breast cancer.

Chaoqian Liu, Yan Guo, Weiwei Wu, Zhenzhen Zhang, Lu Xu, Kainan Wu, Wei Hu, Guoping Liu, Junyi Shi, Cheng Xu and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Combinatorial chemistry & high throughput screening · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Chaoqian LiuDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Yan GuoDepartment of Endocrinology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Weiwei WuBiotecan Medical Diagnostics Co., Ltd, Zhangjiang Center for Translational Medicine, Shanghai 200120, P.R. China.
Zhenzhen ZhangDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Lu XuDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Kainan WuDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Wei HuDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Guoping LiuDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Junyi ShiDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Cheng XuBiotecan Medical Diagnostics Co., Ltd, Zhangjiang Center for Translational Medicine, Shanghai 200120, P.R. China.
Jianwei BiDepartment of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Yuan ShengDepartment of Breast Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
Changhai Hospital · CNSecond Military Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate the expression of olfactomedin 4 (OLFM4) in plasma of patients with breast cancer and its association with diagnosis, metastasis and prognosis of breast cancer. OLFM4 gene expression level of peripheral blood plasma in 60 patients with breast cancer and 26 healthy donors was examined by ELISA. The expression of OLFM4 in tumor tissues of patients with breast cancer was evaluated by immunohistochemistry (protein expression) and reverse transcription-quantitative polymerase chain reaction (mRNA expression), respectively. Circulating tumor cells (CTCs) were detected in a certain set of patients. The expression of OLFM4 in plasma of the overall healthy people was higher compared with patients with breast cancer. The plasma OLFM4 level in patients with breast cancer was consistent with the expression of OLFM4 protein in tumor tissues (R

Indexed as

breast cancercirculating tumor cellsolfactomedin 4plasma

Identifiers

PMID29344255
PMCPMC5755007
OpenAlexW2766978307

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.