Evidence map›Paper›PMID 29344161›Full record

ArticleOncology letters2017

UVB radiation represses CYLD expression in melanocytes.

Silke Kuphal, Nadja Schneider, Ramin Massoumi, Claus Hellerbrand, Anja Katrin Bosserhoff

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Silke KuphalEmil-Fischer-Center, Institute of Biochemistry, Friedrich Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Nadja SchneiderEmil-Fischer-Center, Institute of Biochemistry, Friedrich Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Ramin MassoumiDepartment of Laboratory Medicine, Translational Cancer Research, Lund University, SE-221 00 Lund, Sweden.
Claus HellerbrandEmil-Fischer-Center, Institute of Biochemistry, Friedrich Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Anja Katrin BosserhoffEmil-Fischer-Center, Institute of Biochemistry, Friedrich Alexander University Erlangen-Nuremberg, D-91054 Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DELund University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CYLD lysine 63 deubiquitinase (CYLD) was originally identified as a tumor suppressor that is mutated in familial cylindromatosis. Unlike in cylindromatosis, downregulation of the deubiquitinase CYLD in melanoma, a highly aggressive tumor, is not caused by mutations in the

Indexed as

CYLDERKmelanocytesSNAIL1UVB

Identifiers

PMID29344161
PMCPMC5754916
OpenAlexW2763053731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.