Evidence map›Paper›PMID 29344090›Full record

ArticleMolecular cytogenetics2018

Overexpression of the proneural transcription factor ASCL1 in chronic lymphocytic leukemia with a t(12;14)(q23.2;q32.3).

Theodora Malli, Melanie Rammer, Sabrina Haslinger, Jonathan Burghofer, Sonja Burgstaller, Hans-Christian Boesmueller, Renate Marschon, Wolfgang Kranewitter, Martin Erdel, Sabine Deutschbauer and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Molecular cytogenetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. INSM1 expression in a subset of thoracic malignancies and small round cell tumors: rare potential pitfalls for small cell carcinoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Theodora MalliLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Melanie RammerLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Sabrina HaslingerLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Jonathan BurghoferLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Sonja Burgstaller2Department for Internal Medicine IV, Klinikum Wels-Grieskirchen, Grieskirchner Str. 42, 4600 Wels, Austria.
Hans-Christian BoesmuellerDepartment of Pathology, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Renate MarschonLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Wolfgang KranewitterLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Martin ErdelLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Sabine DeutschbauerLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.
Gerald WebersinkeLaboratory for Molecular Biology and Tumor Cytogenetics, Department of Internal Medicine I, Ordensklinikum Linz GmbH Barmherzige Schwestern, Seilerstaette 4, 4010 Linz, Austria.ORCID 0000-0001-5654-6190
AGO Austria · ATHertie Institute for Clinical Brain Research · DEKlinikum Wels-Grieskirchen · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranslocations of the CASE PRESENTATION: We report on the molecular characterization of a novel t(12;14)(q23.2;q32.3) in CLL. As a consequence of the rearrangement

conclusionWe identified

Indexed as

ASCL1 overexpressionChronic lymphocytic leukemiaExpression microarrayIGH translocationINSM1

Identifiers

PMID29344090
PMCPMC5765657
OpenAlexW2784305853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.