ArticleIranian journal of nursing and midwifery research
The Impact of Normal Saline on the Incidence of Exposure Keratopathy in Patients Hospitalized in Intensive Care Units.
Article in Iranian journal of nursing and midwifery research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Ocular Surface Disorders in ICU Patients: Evidence-Based Nursing Prevention Strategies.Translational vision science & technology · 2025Pooled it
- Effect of Polyethylene Cover for Preventing Corneal Injury in Critically Ill Patients: A Meta-Analysis.Computational and mathematical methods in medicine · 2022Pooled it
- [Effectiveness of the Eye Care Protocol in the Intensive Care Unit Patients: A Randomized Controlled Trial].Journal of Korean Academy of Nursing · 2024Trial
- Initial assessment of a species-specific rebound measurement mode for non-human primates.BMC veterinary research · 2026Article
- Construction of a preventive nursing protocol for eye complications in critically ill patients undergoing prone position ventilation in China: a Delphi study.BMC nursing · 2026Article
- Characteristics and associated risk factors of exposure keratopathy among ventilated patients in intensive care units in JordanAcute and critical care · 2025Article
- [Treatment algorithm: eye care for critically ill patients].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2023Article
- Nurses' perceptions of critically ill patients' eye care: a qualitative study in Iran.BMC nursing · 2023Article
- The effect of implementation of evidence-based eye care protocol for patients in the intensive care units on superficial eye disorders.BMC ophthalmology · 2021Article
- Incidence and related factors of surface eye disorders in traumatic intensive care unit patients in Iran.International journal of burns and trauma · 2021Article
- Effectiveness Of Polyethylene Cover Versus Polyethylene Cover With Artificial Tear Drop To Prevent Dry Eye In Critically Ill Patients: A Randomized Controlled Clinical Trial.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- A Second Look at the Impact of Normal Saline on the Incidence of Exposure Keratopathy.Iranian journal of nursing and midwifery researchArticle
- Exposure keratopathy and its associated risk factors in patients undergoing general anesthesia in nonocular surgeries.Oman journal of ophthalmologyArticle
- The Effects of Passive Blinking on Exposure Keratopathy among Patients in Intensive Care Units.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients in the intensive care unit (ICU) have impaired ocular protective mechanisms that lead to an increased risk of ocular surface diseases including exposure keratopathy (EK). This study was designed to evaluate the effect of normal saline (NS) on the incidence and severity of EK in critically ill patients. MATERIALS AND
methodsThis single-blind randomized controlled trial was conducted on 50 patients admitted to ICUs. The participants were selected through purposive sampling. One eye of each patient, randomly was allocated to intervention group (standard care with NS) and the other eye to control group (standard care). In each patient, one eye (control group) randomly received standard care and the other eye (intervention group) received NS every 6 h in addition to standard care. The presence and severity of keratopathy was assessed daily until day 7 of hospitalization using fluorescein and an ophthalmoscope with cobalt blue filter. Chi-square test was used for statistical analysis in SPSS software.
resultsBefore the study ( first day) there were no statistically significant differences in the incidence and severity of EK between groups. Although, the incidence and severity of EK after the study (7
conclusionsThe use of NS as eye care in patients hospitalized in ICUs can increase the incidence and severity of EK and is not recommended.
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