Evidence map›Paper›PMID 29344027›Full record

ArticleCardiorenal medicine2017

Plasma Volume and Renal Function Predict Six-Month Survival after Hospitalization for Acute Decompensated Heart Failure.

Kenneth C Bilchick, Nathaniel Chishinga, Alex M Parker, David X Zhuo, Mitchell H Rosner, LaVone A Smith, Hunter Mwansa, Jacob N Blackwell, Peter A McCullough, Sula Mazimba

Open access · bronzeAbstract read
In one paragraph

Article in Cardiorenal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Estimated plasma volume status in heart failure: clinical implications and future directions.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kenneth C BilchickDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Nathaniel ChishingaDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Alex M ParkerDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
David X ZhuoDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Mitchell H RosnerDivision of Nephrology, University of Virginia Health System, Charlottesville, Virginia, USA.
LaVone A SmithDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Hunter MwansaSt Vincent Charity Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Jacob N BlackwellDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Peter A McCulloughBaylor University Medical Center, Dallas, Texas, USA.
Sula MazimbaDivision of Cardiovascular Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
University of Virginia Health System · USBaylor University Medical Center · USSt. Vincent Charity Hospital · US

Funding

Cardiac Magnetic Resonance Imaging After Cardiac Resynchronization TherapyR03HL135463 · NHLBI · UNIVERSITY OF VIRGINIA · PI BILCHICK, KENNETH C · 2016 to 2017
$127k
NHLBI NIH HHS R03 HL135463
6 · The paper itself

Abstract

backgroundPlasma volume (PV) is contracted in stable patients with heart failure (HF) due to decongestion strategies. On the other hand, increased PV can adversely affect the trajectory of HF. We therefore examined the effects of increased percentage change in PV (%ΔPV), blood urea nitrogen (BUN), and %ΔPV stratified by BUN and glomerular filtration rate (GFR) on survival after discharge in patients hospitalized for acute decompensated HF (ADHF).

methodsWe used the Strauss-Davis-Rosenbaum formula to calculate the %ΔPV between baseline and hospital discharge in a cohort from the Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness trial (ESCAPE). Kaplan-Meier curves were constructed for survival over 6 months. Cox proportional hazards regression was used to obtain adjusted hazard ratios (HR) and 95% confidence intervals (95% CI) for the associations between survival after discharge and %ΔPV, BUN, and %ΔPV stratified by BUN and GFR.

resultsOf the 324 patients included in our study (age 56.1 ± 13.6 years, 26.5% female), those with increased or no %ΔPV at discharge were less likely to survive at 6 months compared with those having reduced %ΔPV (log rank,

conclusionsIncreased %ΔPV and BUN at discharge predicted worse 6-month survival in patients with ADHF. Decreased %ΔPV with low BUN or high GFR at discharge was associated with improved survival.

Indexed as

Heart failureMortalityPlasma volume

Identifiers

PMID29344027
PMCPMC5757574
OpenAlexW2767076029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.