Evidence map›Paper›PMID 29343988›Full record

ArticleClinical epidemiology2018

Does breast density measured through population-based screening independently increase breast cancer risk in Asian females?

Boyoung Park, Hye Mi Cho, Eun Hye Lee, Seunghoon Song, Mina Suh, Kui Son Choi, Bong Joo Kang, Kyungran Ko, Ann Yi, Hae Kyoung Jung and 2 more

Abstract read
In one paragraph

Article in Clinical epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Breast Cancer Disparities in Asian Women: The Need for Disaggregated Research.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Boyoung ParkNational Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.
Hye Mi ChoNational Cancer Control Institute, National Cancer Center, Goyang, Republic of Korea.
Eun Hye LeeDepartment of Radiology, Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Republic of Korea.
Seunghoon SongNational Cancer Control Institute, National Cancer Center, Goyang, Republic of Korea.
Mina SuhNational Cancer Control Institute, National Cancer Center, Goyang, Republic of Korea.
Kui Son ChoiNational Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.
Bong Joo KangDepartment of Radiology, Seoul St Mary's Hospital, Catholic University of Korea College of Medicine, Seoul, Republic of Korea.
Kyungran KoCenter for Breast Cancer, National Cancer Center Hospital, National Cancer Center, Goyang, Republic of Korea.
Ann YiDepartment of Radiology, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Republic of Korea.
Hae Kyoung JungDepartment of Radiology, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
Joo Hee ChaDepartment of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jae Kwan JunNational Cancer Center Graduate School of Cancer Science and Policy, Goyang, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the effects of breast density on breast cancer risk among women screened via a nationwide mammographic screening program. PATIENTS AND

methodsWe conducted a nested case-control study for a randomly selected population of 1,561 breast cancer patients and 6,002 matched controls from the National Cancer Screening Program. Breast density was measured and recorded by two independent radiologists using the Breast Imaging Reporting and Data System (BI-RADS). Associations between BI-RADS density and breast cancer risk were evaluated according to screening results, time elapsed since receiving non-recall results, age, and menopausal status after adjusting for possible covariates.

resultsBreast cancer risk for women with extremely dense breasts was five times higher (adjusted odds ratio [aOR] =5.0; 95% confidence interval [CI]) =3.7-6.7) than that for women with an almost entirely fatty breast, although the risk differed between recalled women (aOR =3.3, 95% CI =2.3-3.6) and women with non-recalled results (aOR =12.1, 95% CI =6.3-23.3,

conclusionThis study confirmed an increased risk of breast cancer with greater breast density in Korean women which was consistent regardless of BI-RADS assessment category, time interval after initially non-recall results, and menopausal status.

Indexed as

breast cancerbreast densitybreast imaging reporting and data systemnationwide mammographic screening program

Identifiers

PMID29343988
PMCPMC5749627

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.