Evidence map›Paper›PMID 29343807›Full record

ArticleScientific reports2018

House dust mite induced allergic airway disease is attenuated in CD11c

Natalie Eva Nieuwenhuizen, Frank Kirstein, Jennifer Claire Hoving, Frank Brombacher

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. IL-4 acts on skin-derived dendritic cells to promote the TThe Journal of allergy and clinical immunology · 2024
    Article
  2. Piecing Together the Role of IL-4 Receptor Alpha in Allergic Asthma One Cell at a Time.American journal of respiratory cell and molecular biology · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. β2 Integrins-Multi-Functional Leukocyte Receptors in Health and Disease.International journal of molecular sciences · 2020
    Review
  10. IL-4Rα-expressing CD11cJournal of leukocyte biology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Natalie Eva NieuwenhuizenInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town component, University of Cape Town, Cape Town, South Africa. nnieuwen@gmail.com.
Frank KirsteinInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town component, University of Cape Town, Cape Town, South Africa.
Jennifer Claire HovingInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town component, University of Cape Town, Cape Town, South Africa.
Frank BrombacherInternational Centre for Genetic Engineering and Biotechnology (ICGEB), Cape Town component, University of Cape Town, Cape Town, South Africa. brombacherfrank@gmail.com.
South African Medical Research Council · ZAInternational Centre for Genetic Engineering and Biotechnology · ZA

Funding

Wellcome Trust 209293/Z/17/Z
6 · The paper itself

Abstract

The precise mechanisms leading to development of T helper type (Th)2-driven allergic responses are unknown. We aimed to determine how IL-4 receptor alpha (IL-4Rα) signaling on CD11c

Indexed as

AllergensAlum CompoundsAnimalsAsthmaCD11c AntigenCytokinesDendritic CellsEosinophilsHypersensitivityInterleukin-4 Receptor alpha SubunitLungMacrophages, AlveolarMiceMice, Inbred BALB CMice, Inbred C57BLOvalbuminAllergensAlum CompoundsCD11c AntigenCytokinesIl4ra protein, mouseInterleukin-4 Receptor alpha SubunitOvalbuminovalbumin-alumReceptors, Cell Surface

Identifiers

PMID29343807
PMCPMC5772663
OpenAlexW2783734031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.