Evidence map›Paper›PMID 29343800›Full record

ArticleScientific reports2018

Faecal shedding of rotavirus vaccine in Chinese children after vaccination with Lanzhou lamb rotavirus vaccine.

Jin-Song Li, Bing Cao, Han-Chun Gao, Dan-di Li, Lin Lin, Li-Li Li, Na Liu, Zhao-Jun Duan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Global Experience With Rotavirus Vaccines.The Journal of infectious diseases · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. COVID-19: should oral vaccination strategies be given more consideration?Therapeutic advances in vaccines and immunotherapy · 2020
    Article
  13. Current and new rotavirus vaccines.Current opinion in infectious diseases · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jin-Song LiNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China.
Bing CaoHunan Rucheng Rural Commercial Bank CO., Ltd, Hunan, 424104, China.
Han-Chun GaoNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China.
Dan-di LiNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China.
Lin LinNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China.
Li-Li LiNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China.
Na LiuNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China. unali@163.com.
Zhao-Jun DuanNational Institute for Viral Disease Control and Prevention, China CDC, Beijing, 100052, China. zhaojund@126.com.
Chinese Center For Disease Control and Prevention · CNNational Institute for Viral Disease Control and Prevention · CNIndustrial and Commercial Bank of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lanzhou lamb rotavirus vaccine (LLR) is an oral live attenuated vaccine first licensed in China in 2000. To date, > 60 million doses of LLR have been distributed to children. However, very little is known about faecal shedding of LLR in children. Therefore, faecal samples (n = 1,184) were collected from 114 children for 15 days post-vaccination in September-November 2011/2012. Faecal shedding and viral loads were determined by an enzyme immunoassay kit (EIA) and real-time RT-PCR. The complete genome was sequenced and the vaccine strain was isolated by culture in MA104 cells. Approximately 14.0% (16/114) of children had rotavirus-positive samples by EIA for at least 1 day post-vaccination. Viral loads in EIA-positive samples ranged from < 1.0 × 10

Indexed as

Genome, ViralVirus ReplicationAnimalsCell LineChild, PreschoolChinaChlorocebus aethiopsEpithelial CellsFecesFemaleHigh-Throughput Nucleotide SequencingHumansInfantMaleMass VaccinationRotavirusRotavirus Vaccines

Identifiers

PMID29343800
PMCPMC5772666
OpenAlexW2783663318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.