ArticleJournal of the Royal Society, Interface2018
Combining radiation with hyperthermia: a multiscale model informed by
Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- A data assimilation framework to predict the response of glioma cells to radiation.Mathematical biosciences and engineering : MBE · 2023Article
- Temperature processing and distribution in larynx thermal inhalation injury with analogy to human airway cells: a mechanism of protection.American journal of translational research · 2022Article
- A Multi-Compartment Model of Glioma Response to Fractionated Radiation Therapy ParameterizedFrontiers in oncology · 2022Article
- Targeting Cellular DNA Damage Responses in Cancer: An In Vitro-Calibrated Agent-Based Model Simulating Monolayer and Spheroid Treatment Responses to ATR-Inhibiting Drugs.Bulletin of mathematical biology · 2021Article
- A time-resolved experimental-mathematical model for predicting the response of glioma cells to single-dose radiation therapy.Integrative biology : quantitative biosciences from nano to macro · 2021Article
- Towards an Image-Informed Mathematical Model of In Vivo Response to Fractionated Radiation Therapy.Cancers · 2021Article
- Mathematical model for the thermal enhancement of radiation response: thermodynamic approach.Scientific reports · 2021Article
- The interplay of blood flow and temperature in regional hyperthermia: a mathematical approach.Royal Society open science · 2021Article
- Mathematical modelling reveals cellular dynamics within tumour spheroids.PLoS computational biology · 2020Article
- Combining hypoxia-activated prodrugs and radiotherapy in silico: Impact of treatment scheduling and the intra-tumoural oxygen landscape.PLoS computational biology · 2020Article
- Forecasting tumor and vasculature response dynamics to radiation therapy via image based mathematical modeling.Radiation oncology (London, England) · 2020Article
- A cellular automaton model for spheroid response to radiation and hyperthermia treatments.Scientific reports · 2019Article
- Biomedical Applications of Hyaluronic Acid-Based Nanomaterials in Hyperthermic Cancer Therapy.Pharmaceutics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Combined radiotherapy and hyperthermia offer great potential for the successful treatment of radio-resistant tumours through thermo-radiosensitization. Tumour response heterogeneity, due to intrinsic, or micro-environmentally induced factors, may greatly influence treatment outcome, but is difficult to account for using traditional treatment planning approaches. Systems oncology simulation, using mathematical models designed to predict tumour growth and treatment response, provides a powerful tool for analysis and optimization of combined treatments. We present a framework that simulates such combination treatments on a cellular level. This multiscale hybrid cellular automaton simulates large cell populations (up to 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.