Evidence map›Paper›PMID 29343626›Full record

ReviewScience translational medicine2018

Engineering precision biomaterials for personalized medicine.

Brian A Aguado, Joseph C Grim, Adrianne M Rosales, Jana J Watson-Capps, Kristi S Anseth

Abstract readReview
In one paragraph

Review in Science translational medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Toward Sex-Specific Biomaterials Innovation: A Perspective.ACS biomaterials science & engineering · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Cadaveric Adipose-Derived Stem Cells for Regenerative Medicine and Research.International journal of molecular sciences · 2023
    Article
  20. Review

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Brian A AguadoDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0002-4449-9806
Joseph C GrimDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA.
Adrianne M RosalesDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0003-0207-7661
Jana J Watson-CappsBioFrontiers Institute, University of Colorado, Boulder, CO 80309, USA.ORCID 0000-0001-5118-4928
Kristi S AnsethDepartment of Chemical and Biological Engineering, University of Colorado, Boulder, CO 80309, USA. kristi.anseth@colorado.edu.ORCID 0000-0002-4449-9806

Funding

Hydrogels to Study Synergistic Effects of Signaling Factors and Matrix Mechanics on Valve Disease ProgressionR01HL132353 · NHLBI · UNIVERSITY OF COLORADO · PI ANSETH, KRISTI S. · 2017 to 2020
$1.4M
Mechanical Dosing Effects on MSCsR21AR067469 · NIAMS · UNIVERSITY OF COLORADO · PI ANSETH, KRISTI S. · 2015 to 2016
$361k
Development of a nanotherapy for aortic valve stenosisF32HL137256 · NHLBI · UNIVERSITY OF COLORADO · PI AGUADO, BRIAN ALBERTO · 2017 to 2019
$134k
Howard Hughes Medical InstituteNHLBI NIH HHS F32 HL137256NHLBI NIH HHS R01 HL132353NIAMS NIH HHS R21 AR067469
6 · The paper itself

Abstract

As the demand for precision medicine continues to rise, the "one-size-fits-all" approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.

Indexed as

Biocompatible MaterialsHumansPrecision MedicineBiocompatible Materials

Identifiers

PMID29343626
PMCPMC6079507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.