Evidence map›Paper›PMID 29343573›Full record

ArticleJournal of virology2018

Porcine Mx1 Protein Inhibits Classical Swine Fever Virus Replication by Targeting Nonstructural Protein NS5B.

Jing Zhou, Jing Chen, Xiao-Min Zhang, Zhi-Can Gao, Chun-Chun Liu, Yun-Na Zhang, Jin-Xiu Hou, Zhao-Yao Li, Lin Kan, Wen-Liang Li and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Article
  7. Article
  8. Pestiviruses infection: Interferon-virus mutual regulation.Frontiers in cellular and infection microbiology · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Frontiers in veterinary science · 2020
    Article
  18. Article
  19. Article
  20. Classical Swine Fever in China-An Update Minireview.Frontiers in veterinary science · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jing Zhou *College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Jing Chen *College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Xiao-Min ZhangRugao Animal Husbandry and Veterinary Station, Rugao, China.
Zhi-Can GaoCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Chun-Chun LiuCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Yun-Na ZhangCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Jin-Xiu HouCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Zhao-Yao LiCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Lin KanCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Wen-Liang LiInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.
Bin ZhouCollege of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China zhoubin@njau.edu.cn.
Nanjing Agricultural University · CNJiangsu Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mx proteins are interferon (IFN)-induced GTPases that have broad antiviral activity against a wide range of RNA and DNA viruses; they belong to the dynamin superfamily of large GTPases. In this study, we confirmed the anti-classical swine fever virus (CSFV) activity of porcine Mx1

Indexed as

Amino Acid SubstitutionAnimalsClassical Swine Fever VirusHEK293 CellsHumansMutation, MissenseMyxovirus Resistance ProteinsSwineViral Nonstructural ProteinsVirus ReplicationMyxovirus Resistance ProteinsViral Nonstructural Proteinsantivirusclassical swine fever virus (CSFV)mutantsnonstructural protein 5B (NS5B)porcine Mx1 (poMx1)

Identifiers

PMID29343573
PMCPMC5972896
OpenAlexW2783767647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.