Evidence map›Paper›PMID 29343559›Full record

ArticleBiology letters2018

A genetic locus for paranoia.

Bernard Crespi, Silven Read, Iiro Salminen, Peter Hurd

Open access · bronzeAbstract read
In one paragraph

Article in Biology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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  8. A genetic locus for paranoia.Biology letters · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Bernard CrespiDepartment of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, Canada V5A 1S6 crespi@sfu.ca.ORCID 0000-0002-0362-392X
Silven ReadDepartment of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, Canada V5A 1S6.
Iiro SalminenDepartment of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, Canada V5A 1S6.
Peter HurdDepartment of Psychology and Centre for Neuroscience, University of Alberta, Edmonton, Canada T6G 2R3.
Simon Fraser University · CAUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The psychological effects of brain-expressed imprinted genes in humans are virtually unknown. Prader-Willi syndrome (PWS) is a neurogenetic condition mediated by genomic imprinting, which involves high rates of psychosis characterized by hallucinations and paranoia, as well as autism. Altered expression of two brain-expressed imprinted genes,

Indexed as

AdultFemaleGenotypeHumansIntracellular Signaling Peptides and ProteinsIntrinsically Disordered ProteinsMaleModels, GeneticParanoid DisordersPolymorphism, Single NucleotideProteinsSurveys and QuestionnairesTumor Suppressor ProteinsYoung AdultIntracellular Signaling Peptides and ProteinsIntrinsically Disordered ProteinsMAGEL2 protein, humanNDN protein, humanProteinsTumor Suppressor Proteinsgenomic imprintingmagel2necdinparanoiaPrader–Willi

Identifiers

PMID29343559
PMCPMC5803597
OpenAlexW2784138807

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.