Evidence map›Paper›PMID 29343539›Full record

ReviewJournal of clinical microbiology2018

Buruli Ulcer: Review of a Neglected Skin Mycobacterial Disease.

Jeannette Guarner

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05169554 (Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05169554 phase2unknown statusnot on this mapstarted 2021, after this paper: background citation

Beta-Lactam Containing Regimen for the Shortening of Buruli Ulcer Disease Therapy: Comparison of 8 Weeks Standard Therapy (Rifampicin Plus Clarithromycin) vs. 4 Weeks Standard Plus Amoxicillin/Clavulanate Therapy [RC8 vs. RCA4]

TypeinterventionalSponsorFundacion Agencia Aragonesa para la Investigacion y Desarrollo (ARAID)Ran2021 to 2026Enrolled140ConditionsBuruli UlcerArmsStandard [RC8]: rifampicin plus clarithromycin (RC) therapy for 8 weeks., Investigational [RCA4]: standard (RC) plus amoxicillin/clavulanate (A) for 4 weeks.
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. AtypicalJournal of clinical medicine · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Bacterial diversity in Buruli ulcer lesions in Ghana.Journal of clinical tuberculosis and other mycobacterial diseases · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Pharmacologic management ofExpert review of clinical pharmacology · 2020
    Review
  19. Emerging infections: mimickers of common patterns seen in dermatopathology.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jeannette GuarnerDepartment of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA jguarne@emory.edu.
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Buruli ulcer is caused by

Indexed as

Africa, WesternAnti-Bacterial AgentsBuruli UlcerClarithromycinHumansMacrolidesMycobacterium InfectionsMycobacterium ulceransNeglected DiseasesPolymerase Chain ReactionRifampinSkin Diseases, BacterialStreptomycinAnti-Bacterial AgentsClarithromycinMacrolidesmycolactoneRifampinStreptomycinBuruli ulcerMycobacterium ulceransneglected diseaseskin mycobacteria

Identifiers

PMID29343539
PMCPMC5869816
OpenAlexW2782922779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.