ArticleParasites & vectors2018
First molecular detection and genetic characterization of Coxiella burnetii in Zambian dogs and rodents.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Unveiling the hidden threats: a review of pathogen diversity and public health risks from bats, rodents, and non-human primates in Zambia (1990-2022).Frontiers in public health · 2024Pooled it
- Surveillance forOne health (Amsterdam, Netherlands) · 2026Article
- Rodent-borne pathogens as economic and zoonotic health threat to livestock farming: a review.One health (Amsterdam, Netherlands) · 2026Review
- Pathogen screening of Zambian ticks: new insights on the occurrence of tick-borne pathogens in the country.Parasites & vectors · 2026Article
- Molecular Detection and Prevalence ofPathogens (Basel, Switzerland) · 2025Article
- Coxiellosis in Dogs-A Hitherto Masked Zoonosis in India: An Insight From Seromolecular Investigation and Risk Factor Analysis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Article
- Evidence of multiple bacterial, viral, and parasitic infectious disease agents inInfection ecology & epidemiology · 2025Article
- Serological and molecular prevalences and phylogenetic analysis ofVeterinary world · 2024Article
- Molecular surveillance of zoonotic pathogens from wild rodents in the Republic of Korea.PLoS neglected tropical diseases · 2024Article
- Serosurvey ofTropical medicine and infectious disease · 2024Article
- Prevalence and risk factors of coxiellosis in meat goat herds: an epidemiological investigation in Northeastern Thailand.International journal of veterinary science and medicine · 2024Article
- Distribution and Prevalence ofInfectious disease reports · 2023Review
- Current knowledge of vector-borne zoonotic pathogens in Zambia: A clarion call to scaling-up "One Health" research in the wake of emerging and re-emerging infectious diseases.PLoS neglected tropical diseases · 2022Review
- Detection and distribution of zoonotic pathogens in wild Norway rats (New microbes and new infections · 2021Article
- Molecular Detection and Genotyping ofPathogens (Basel, Switzerland) · 2021Article
- Molecular detection of Coxiella burnetii infection in small mammals from Moshi Rural and Urban Districts, northern Tanzania.Veterinary medicine and science · 2021Article
- Detection of Multiple Intracellular Bacterial Pathogens inPathogens (Basel, Switzerland) · 2021Article
- Molecular Detection and Characterization ofFrontiers in veterinary science · 2021Article
- Article
- Retrospective Study on the Occurrence of Antibodies againstPathogens (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Coxiella burnetii, the causative agent of Q fever, is a zoonotic pathogen associated with sylvatic or domestic transmission cycles, with rodents being suspected to link the two transmission cycles. Infection and subsequent disease in humans has historically been associated with contact with infected livestock, especially sheep. However, recently there have been reports of Q fever outbreaks associated with contact with infected rodents and dogs. Studies exploring the potential role of these animal hosts in the epidemiology of Q fever in many developing countries in Africa are very limited. This study aimed to determine the potential role of rodents and dogs in the epidemiological cycle of C. burnetti in Zambia. Using pathogen-specific polymerase chain reaction assays targeting the 16S rRNA gene, C. burnetii was detected for the first time in 45% of rodents (9/20), in one shrew and in 10% of domestic dogs (15/150) screened in Zambia. Phylogenetic characterization of six samples based on the isocitrate synthase gene revealed that the strains were similar to a group of isolates from chronic human Q fever patients, goats and rodents reported in multiple continents. Considering the close proximity of domestic dogs and rodents to humans, especially in resource-limited communities, the presence of C. burnetii in these animals could be of significant public health importance. It is thus important to determine the burden of Q fever in humans in such resource-limited communities where there is close contact between humans, rodents and dogs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.