Evidence map›Paper›PMID 29342960›Full record

ArticleBiosensors2018

A Low-Cost Inkjet-Printed Aptamer-Based Electrochemical Biosensor for the Selective Detection of Lysozyme.

Niazul Islam Khan, Alec G Maddaus, Edward Song

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Biosensors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

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  11. Aptamers isolated against mosquito-borne pathogens.World journal of microbiology & biotechnology · 2021
    Review
  12. Using Simple-Structured Split Aptamer for Gold Nanoparticle-based Colorimetric Detection of Estradiol.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Niazul Islam KhanDepartment of Electrical and Computer Engineering, University of New Hampshire, Durham, NH 03824, USA. mk1125@wildcats.unh.edu.
Alec G MaddausDepartment of Chemical Engineering, University of New Hampshire, Durham, NH 03824, USA. agm11@wildcats.unh.edu.
Edward SongDepartment of Electrical and Computer Engineering, University of New Hampshire, Durham, NH 03824, USA. edward.song@unh.edu.ORCID 0000-0003-1702-4044
University of New Hampshire · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, inkjet-printing has gained increased popularity in applications such as flexible electronics and disposable sensors, as well as in wearable sensors because of its multifarious advantages. This work presents a novel, low-cost immobilization technique using inkjet-printing for the development of an aptamer-based biosensor for the detection of lysozyme, an important biomarker in various disease diagnosis. The strong affinity between the carbon nanotube (CNT) and the single-stranded DNA is exploited to immobilize the aptamers onto the working electrode by printing the ink containing the dispersion of CNT-aptamer complex. The inkjet-printing method enables aptamer density control, as well as high resolution patternability. Our developed sensor shows a detection limit of 90 ng/mL with high target selectivity against other proteins. The sensor also demonstrates a shelf-life for a reasonable period. This technology has potential for applications in developing low-cost point-of-care diagnostic testing kits for home healthcare.

Indexed as

AnimalsAptamers, NucleotideBiosensing TechniquesChickensElectrochemical TechniquesElectrodesMuramidasePrintingAptamers, NucleotideMuramidaseaptamerbiosensorelectrochemical impedance spectroscopyinkjet printinglysozymepoint-of-care

Identifiers

PMID29342960
PMCPMC5872055
OpenAlexW2782932130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.