Evidence map›Paper›PMID 29342867›Full record

ArticleNutrients2018

A Longitudinal Study of 25-Hydroxy Vitamin D and Parathyroid Hormone Status throughout Pregnancy and Exclusive Lactation in New Zealand Mothers and Their Infants at 45° S.

Benjamin J Wheeler, Barry J Taylor, Michel de Lange, Michelle J Harper, Shirley Jones, Adel Mekhail, Lisa A Houghton

Abstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Dental Consequences of Vitamin D Deficiency during Pregnancy and Early Infancy-An Observational Study.International journal of environmental research and public health · 2022
    Observational
  9. The etiology of preeclampsia.American journal of obstetrics and gynecology · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. A Brief History of Nutritional Rickets.Frontiers in endocrinology · 2019
    Review
  18. Article
  19. The Role of Vitamin D in Fertility and during Pregnancy and Lactation: A Review of Clinical Data.International journal of environmental research and public health · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Benjamin J WheelerDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand. Ben.wheeler@otago.ac.nz.ORCID 0000-0003-3348-5238
Barry J TaylorDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand. barry.taylor@otago.ac.nz.
Michel de LangeDepartment Preventative and Social Medicine, University of Otago, Dunedin 9054, New Zealand. michel.delange@otago.ac.nz.
Michelle J HarperDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand. michelle.harper@otago.ac.nz.
Shirley JonesDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand. shirley.jones@otago.ac.nz.
Adel MekhailDepartment of Women's and Children's Health, Dunedin School of Medicine, University of Otago, Dunedin 9054, New Zealand. adel.mekhail@southerndhb.govt.nz.
Lisa A HoughtonDepartment of Human Nutrition, University of Otago, Dunedin 9054, New Zealand. lisa.houghton@otago.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D status and associated metabolism during pregnancy and lactation have been assessed in only a limited number of longitudinal studies, all from the northern hemisphere, with no infant data concurrently reported. Therefore, we aimed to describe longitudinal maternal and infant 25-hydroxy vitamin D (25OHD) and parathyroid hormone (PTH) status during pregnancy and up to 5 months postnatal age, in New Zealand women and their infants living at 45° S latitude. Between September 2011 and June 2013, 126 pregnant women intending to exclusively breastfeed for at least 20 weeks were recruited. Longitudinal data were collected at three time-points spanning pregnancy, and following birth and at 20 weeks postpartum. Vitamin D deficiency (25OHD < 50 nmol/L) was common, found at one or more time-points in 65% and 76% of mothers and their infants, respectively. Mean cord 25OHD was 41 nmol/L, and three infants exhibited secondary hyperparathyroidism by postnatal week 20. Maternal late pregnancy 25OHD (gestation 32-38 weeks) was closely correlated with infant cord 25OHD,

Indexed as

LactationDietDietary SupplementsDose-Response Relationship, DrugFemaleHumansInfantLongitudinal StudiesMothersNew ZealandParathyroid HormonePostpartum PeriodPregnancySeasonsVitamin DVitamin D Deficiency25-hydroxyvitamin DParathyroid HormoneVitamin Dbreastfeedinginfantlactationparathyroid hormonepregnancyvitamin D

Identifiers

PMID29342867
PMCPMC5793314

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.