Trial reportEnvironmental health perspectives2018
Fine Particulate Air Pollution and the Expression of microRNAs and Circulating Cytokines Relevant to Inflammation, Coagulation, and Vasoconstriction.
Trial report in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 180 citations in OpenAlex.
- Effectiveness of indoor air purification intervention in improving cardiovascular health: A systematic review and meta-analysis of randomized controlled trials.The Science of the total environment · 2021Pooled it
- The short- and long-term associations of particulate matter with inflammation and blood coagulation markers: A meta-analysis.Environmental pollution (Barking, Essex : 1987) · 2020Pooled it
- The Impact of Air Pollution on Our Epigenome: How Far Is the Evidence? (A Systematic Review).Current environmental health reports · 2018Pooled it
- Cardiovascular benefits of air purifier in patients with stable coronary artery disease: A randomized single-blind crossover study.Frontiers in public health · 2022Trial
- Climate Change-Mediated Temperature Extremes: Effects on the Immune System and Associations with Immune-Related Diseases.Clinical reviews in allergy & immunology · 2026Review
- Health Benefits of Air Purification: A Systematic Review.Environment & health (Washington, D.C.) · 2026Review
- Regional and size-dependent effects of ambient agricultural particulate matter on Ah-receptor activity and inflammatory responses in human U937 macrophages.Inhalation toxicology · 2026Article
- Immune Dysregulation and Community Health Factors in Maternal and Childhood Leprosy: A Partial Least Squares-Structural Equation Modelling Study.Infection & chemotherapy · 2026Article
- The impact of portable air cleaners on indoor particulate matter concentrations and perceptions of indoor air quality: a randomized crossover trial in three multifamily buildings.Journal of exposure science & environmental epidemiology · 2026Article
- From Signal to Systems Change: The Convergence of Epidemiology and Implementation Science in Precision Cardiovascular Medicine.Circulation. Population health and outcomes · 2026Article
- Short-term PMBMC public health · 2026Article
- Cancer and Cardiovascular Disease: Shared Risk Factors, Mechanisms, and Clinical Implications: JACC: CardioOncology State-of-the-Art Review.JACC. CardioOncology · 2025Review
- Personal exposure to air pollutants and immune system biomarkers in pregnant women.Scientific reports · 2025Article
- Anti-Inflammasome Effect of Impressic Acid on Diesel Exhaust Particulate Matter-Induced NLRP1 Inflammasome via the Keap1/p62/Nrf2-Signaling Pathway in Keratinocytes.Antioxidants (Basel, Switzerland) · 2025Article
- Environmental pollutants and atherosclerosis: Epigenetic mechanisms linking genetic risk and disease.Atherosclerosis · 2025Review
- Effect of PMScientific reports · 2025Article
- Article
- Epigenetics of cardiomyopathies: the next frontier.Heart failure reviews · 2025Review
- Supramolecular nanotherapeutics based on cucurbiturils.Journal of nanobiotechnology · 2024Review
- Air Pollution and Osteoporosis.Current osteoporosis reports · 2024Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroRNAs (miRNAs) are a key factor in epigenetic regulation of gene expression, but miRNA responses to fine particulate matter (PM
objectiveWe explored the potential influence of PM
methodsWe designed a double-blind, randomized crossover study in which true and sham air purifiers were used to expose 55 healthy young adult students in Shanghai, China, to reduced or ambient levels of indoor PM
resultsThe findings were generally consistent for associations with the intervention and for associations with an interquartile range increase in time-weighted PM
conclusionsOur findings require confirmation but suggest that effects of PM
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.